DeStephano D B, Wesley J R, Heidelberger K P, Hutchinson R J, Blane C E, Coran A G
Pediatr Pathol. 1985;4(3-4):291-302. doi: 10.3109/15513818509026902.
A malignant cystic neoplasm in the liver of a 6-month-old girl is reported. The neoplasm has unique clinical and morphological features, and despite ultrastructural and immunohistochemical studies, the tumor could not be clearly classified as any known primary hepatic neoplasm of infancy. A differentiated cystic component of the neoplasm had features of cystic peritoneal mesothelioma. Alpha-1-antitrypsin and alpha-fetoprotein were demonstrated in solid, anaplastic portions of the recurrent tumor by immunohistochemistry. The neoplasm recurred after surgical resection and proved fatal 11 months following diagnosis, despite multiple courses of chemotherapy.
报告了一名6个月大女童肝脏中的恶性囊性肿瘤。该肿瘤具有独特的临床和形态学特征，尽管进行了超微结构和免疫组织化学研究，但仍无法明确将其归类为任何已知的婴儿原发性肝脏肿瘤。肿瘤的分化囊性成分具有囊性腹膜间皮瘤的特征。通过免疫组织化学在复发性肿瘤的实性、间变部分检测到α-1-抗胰蛋白酶和甲胎蛋白。手术切除后肿瘤复发，尽管进行了多疗程化疗，但在诊断后11个月死亡。
