Lang Andrew, Chaudhri Preeti
Department of Histopathology, PathLinks, Lincoln County Hospital, Greetwell Road, Lincoln, Lincolnshire, UK.
J Surg Case Rep. 2019 Jan 24;2019(1):rjy361. doi: 10.1093/jscr/rjy361. eCollection 2019 Jan.
Benign multicystic mesothelioma is an extremely rare neoplasm usually arising from the visceral mesothelium of the peritoneal cavity typically presenting in young to middle-aged women. It has been deemed an indolent tumour with a possible heritable nature, but also a possible reactive neoplasm secondary to trauma. Diagnosis relies on identifying characteristic histology of cysts separated by loose connective tissue stroma and lined by pale, flat or cuboidal mesothelial cells. A 74-year-old male presented with a painless, enlarging scrotal swelling thought to be either an epididymal cyst or hydrocele. He underwent radical orchiectomy and benign multicystic mesothelioma of the tunica vaginalis was characterized on macroscopy and microscopic examination. The potential for malignant transformation of these tumours has not been demonstrated, but they are known to recur. This infrequent presentation of a rare and poorly understood tumour with description of histologic findings may allow for improved diagnosis in other cases.
良性多囊性间皮瘤是一种极为罕见的肿瘤，通常起源于腹膜腔的脏层间皮，多见于年轻至中年女性。它被认为是一种生长缓慢的肿瘤，可能具有遗传性，也可能是创伤后的反应性肿瘤。诊断依赖于识别由疏松结缔组织间质分隔、内衬淡色、扁平或立方形间皮细胞的囊肿的特征性组织学表现。一名74岁男性因无痛性、逐渐增大的阴囊肿物就诊，考虑为附睾囊肿或鞘膜积液。他接受了根治性睾丸切除术，通过大体检查和显微镜检查确诊为鞘膜良性多囊性间皮瘤。这些肿瘤尚未被证实有恶变潜能，但已知会复发。这种罕见且了解甚少的肿瘤的不常见表现以及组织学结果的描述可能有助于提高其他病例的诊断水平。
