Department of Cardiovascular Medicine, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China.
Department of Cardiovascular Medicine, Jiu jiang NO.1 People's Hospital, Jiujiang, 332000, China.
J Health Popul Nutr. 2024 Aug 16;43(1):123. doi: 10.1186/s41043-024-00614-3.
While body mass index (BMI) defines obesity as a well-established risk factor for cardiovascular disease, the paradoxical theory of BMI suggests that obesity may indeed have a favorable impact on the prognosis of cardiovascular disease. Therefore, this study aims to assess the correlation between body shape index (ABSI), which is a novel measure of obesity, and coronary heart disease (CHD) among obese individuals in the United States.
The data from the National Health and Nutrition Examination Survey (NHANES) were evaluated by us for 5046 patients. We assessed the exposure variable ABSI, which includes waist circumference (WC), height, and BMI. The outcome variable was CHD.
The cross-sectional study included a total of 5046 obese adults aged over 20 years, with an average age (standard deviation: SD) of 49.86 (16.24) years and a male proportion of 44.57%.The odds ratio (OR) values for CHD in Model 1, Model 2, 3 were found to be 2.45 (95%CI: 2.12, 2.83), 1.53 (95%CI:1.30, 1.81) and 1.31 (95%CI:1.09, 1.56) per SD increase in ABSI, respectively. In the fully adjusted model, we designated participants in the T1 group as the reference group. Our findings indicate a significant increase in the prevalence of CHD (OR:1.82, 95%CI: 1.07-3.10) only within the T3 group. Although there is an increased prevalence of CHD (OR:1.32, 95%CI: 0.77-2.29) in the T2 group, no statistically significant difference was observed.
The increase in ABSI is strongly associated with the rise in CHD prevalence among obese individuals in the United States.
虽然体重指数（BMI）将肥胖定义为心血管疾病的一个既定危险因素，但 BMI 的矛盾理论表明，肥胖实际上可能对心血管疾病的预后产生有利影响。因此，本研究旨在评估身体形状指数（ABSI）与美国肥胖人群中心血管疾病（CHD）之间的相关性，ABSI 是一种新的肥胖衡量标准。
我们评估了来自全国健康和营养检查调查（NHANES）的数据，其中包含 5046 名患者。我们评估了暴露变量 ABSI，它包括腰围（WC）、身高和 BMI。结果变量是 CHD。
这项横断面研究共纳入 5046 名年龄超过 20 岁的肥胖成年人，平均年龄（标准差：SD）为 49.86（16.24）岁，男性比例为 44.57%。在模型 1、模型 2、3 中，ABSI 每增加一个标准差，CHD 的比值比（OR）值分别为 2.45（95%CI：2.12，2.83）、1.53（95%CI：1.30，1.81）和 1.31（95%CI：1.09，1.56）。在完全调整的模型中，我们将 T1 组的参与者指定为参考组。我们的研究结果表明，仅在 T3 组中，ABSI 增加与 CHD 患病率显著增加（OR：1.82，95%CI：1.07-3.10）相关。虽然 T2 组的 CHD 患病率（OR：1.32，95%CI：0.77-2.29）有所增加，但无统计学差异。
ABSI 的增加与美国肥胖人群中 CHD 患病率的上升密切相关。
