Department of Child and Adolescent Mental Disorder, Affiliated Psychological Hospital of Anhui Medical University, Hefei, China; Department of Psychiatry, Anhui Mental Health Center, Hefei, China.
Department of Psychiatry, Chao Hu Hospital of Anhui Medical University, Hefei, China.
Psychiatry Res Neuroimaging. 2024 Oct;344:111867. doi: 10.1016/j.pscychresns.2024.111867. Epub 2024 Aug 10.
Studies have revealed that somatization symptoms are associated with emotional memory in adolescents with depressive disorders. This study investigated somatization symptoms and emotional memory among adolescents with depressive disorders using low-frequency amplitude fluctuations (ALFF). Participants were categorized into the somatization symptoms (FSS) group, non-FSS group and healthy control group (HC). The correctness of negative picture re-recognition was higher in the FFS and HC group than in the non-FSS group. The right superior occipital gyrus and right inferior temporal gyrus were significantly larger in the FSS group than those in the non-FSS and HC groups. Additionally, the ALFF in the superior occipital and inferior temporal gyrus were positively correlated with CSI score. Furthermore, the ALFF values in the temporal region positively correlated with correct negative image re-recognition. The negative image re-recognition rate was positively correlated with the ALFF in the left and right middle occipital gyri. These findings indicated that somatization symptoms in adolescent depression are associated with the superior occipital gyrus and inferior temporal gyrus. Notably, somatization symptoms play a role in memory bias within depressive disorders, with middle occipital and inferior temporal gyri potentially serving as significant brain regions.
研究表明，躯体化症状与抑郁障碍青少年的情绪记忆有关。本研究采用低频振幅波动（ALFF）探讨抑郁障碍青少年的躯体化症状和情绪记忆。参与者分为躯体化症状（FSS）组、非 FSS 组和健康对照组（HC）。FSS 组和 HC 组对负性图片的再识别正确率高于非 FSS 组。FSS 组右侧顶上回和右侧颞下回明显大于非 FSS 组和 HC 组。此外，顶上回和颞下回的 ALFF 与 CSI 评分呈正相关。此外，颞区的 ALFF 值与正确的负性图像再识别呈正相关。负性图像再识别率与左右中枕叶的 ALFF 值呈正相关。这些发现表明，青少年抑郁症中的躯体化症状与顶上回和颞下回有关。值得注意的是，躯体化症状在抑郁障碍的记忆偏差中起作用，中枕叶和颞下回可能是重要的脑区。
