Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, People's Republic of China; Jiangsu Province Key Laboratory of Green Biomass-based Fuels and Chemicals, Nanjing 210037, People's Republic of China.
Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, People's Republic of China; Jiangsu Province Key Laboratory of Green Biomass-based Fuels and Chemicals, Nanjing 210037, People's Republic of China.
Food Chem. 2024 Dec 15;461:140799. doi: 10.1016/j.foodchem.2024.140799. Epub 2024 Aug 10.
Plant secondary metabolites have attracted considerable attention due to the increasing demand for finite fossil resources and environmental concerns. However, the biosynthesis of aromatic aldehydes or alcohols from renewable resources remains challenging and costly. This study explores a novel approach performed by the aromatic catabolizing organism Rhizopus oryzae, which enables a ferulic acid-activated co-production of 4-vinyl guaiacol (4-VG) and fumaric acid. The strain produced 4.60 g/L 4-VG and 11.25 g/L fumaric acid from a mixed carbon source of glucose and xylose, suggesting that this new pathway allows the potential production of natural 4-VG from low-cost substrates. This green route, which utilizes Rhizopus oryzae's ability to efficiently convert various renewable resources into valuable chemicals, paves the way for improved catalytic efficiency in 4-VG production.
由于对有限的化石资源的需求不断增加以及对环境问题的关注，植物次生代谢产物引起了相当大的关注。然而，从可再生资源生物合成芳香醛或醇仍然具有挑战性和成本高昂。本研究探索了芳香分解生物体米根霉（Rhizopus oryzae）执行的一种新方法，该方法能够使阿魏酸激活 4-乙烯基愈创木酚（4-VG）和富马酸的共生产。该菌株从葡萄糖和木糖的混合碳源中生产出 4.60 g/L 的 4-VG 和 11.25 g/L 的富马酸，表明这条新途径可从低成本的基质中潜在地生产天然 4-VG。这种绿色途径利用了米根霉将各种可再生资源高效转化为有价值的化学物质的能力，为提高 4-VG 生产的催化效率铺平了道路。
