Department of Chemistry, Iran University of Science and Technology, Tehran, Iran.
Department of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
J Chromatogr A. 2024 Sep 27;1733:465240. doi: 10.1016/j.chroma.2024.465240. Epub 2024 Aug 7.
Supercritical fluid extraction (SFE) stands out as an incredibly efficient, environmentally conscious, and fast method for obtaining essential oils (EOs) from plants. These EOs are abundant in aromatic compounds that play a crucial role in various industries such as food, fragrances, cosmetics, perfumery, pharmaceuticals, and healthcare. While there is a wealth of existing literature on using supercritical fluids for extracting plant essential oils, there's still much to explore in terms of combining different techniques to enhance the SFE process. This comprehensive review presents a sophisticated framework that merges SFE with EO extraction methods. This inclusive categorization encompasses a range of methods, including the integration of pressurized liquid processes, ultrasound assistance, steam distillation integration, microfluidic techniques, enzyme integration, adsorbent facilitation, supercritical antisolvent treatments, molecular distillation, microwave assistance, milling process and mechanical pressing integration. Throughout this in-depth exploration, we not only elucidate these combined techniques but also engage in a thoughtful discussion about the challenges they entail and the array of opportunities they offer within the realm of SFE for EOs. By dissecting these complexities, our objective is to tackle the current challenges associated with enhancing SFE for commercial purposes. This endeavor will not only streamline the production of premium-grade essential oils with improved safety measures but also pave the way for novel applications in various fields.
超临界流体萃取(SFE)是一种非常高效、环保且快速的方法,可从植物中提取精油(EOs)。这些精油富含芳香化合物,在食品、香料、化妆品、香水、制药和医疗保健等多个行业中发挥着关键作用。虽然已有大量关于使用超临界流体提取植物精油的文献,但在结合不同技术以增强 SFE 工艺方面仍有许多值得探索的地方。本综述提供了一个复杂的框架,将 SFE 与 EO 提取方法结合在一起。这种综合分类包括多种方法,包括加压液体工艺的整合、超声辅助、蒸汽蒸馏整合、微流控技术、酶整合、吸附剂促进、超临界抗溶剂处理、分子蒸馏、微波辅助、研磨工艺和机械压制整合。在深入探讨的过程中,我们不仅阐明了这些组合技术,还深入探讨了它们所带来的挑战以及在 SFE 领域为 EOs 提供的各种机会。通过剖析这些复杂性,我们的目标是解决与增强 SFE 以实现商业目的相关的当前挑战。这一努力不仅将简化优质精油的生产,并采取改进的安全措施,还将为各个领域的新应用铺平道路。