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三位被提名诺贝尔奖的皮肤科医生:阿尔伯特·奈瑟、埃里希·霍夫曼和亚伦·B·勒纳。

Three dermatologists who were nominated for a Nobel Prize: Albert Neisser, Erich Hoffmann, and Aaron B. Lerner.

作者信息

Hoenig Leonard J, Parish Lawrence Charles

机构信息

Private Practice, Pembroke Pines, Florida, USA.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Clin Dermatol. 2025 Mar-Apr;43(2):253-258. doi: 10.1016/j.clindermatol.2024.08.005. Epub 2024 Aug 16.

DOI:10.1016/j.clindermatol.2024.08.005
PMID:39154666
Abstract

During the past 125 years, three dermatologists have been nominated for the Nobel Prize in Physiology or Medicine: Albert Neisser (1855-1916), Erich Hoffmann (1868-1959), and Aaron B. Lerner (1920-2007). Neisser was nominated 22 times for his discovery of the gonococcus and for his work on the serologic testing for syphilis through complement fixation. Hoffmann was nominated three times for his role in the discovery of Treponema pallidum. Lerner was nominated twice, once for his work on melanocyte-stimulating hormone and a second time for his work on melatonin. Although neither Neisser, Hoffmann, nor Lerner won the Nobel Prize, it is still a notable accomplishment that each of them was nominated multiple times for this prestigious award. This contribution highlights the lives and careers of these three distinguished dermatologists, including the landmark discoveries they made that led to their being nominated for a Nobel Prize. As of 2023, there were 114 Nobel Prizes in Physiology or Medicine awarded to 227 individuals, none of whom were dermatologists. There were, however, three distinguished dermatologists who were nominated for this illustrious prize: Albert Neisser (1855-1916), Erich Hoffmann (1868-1959), and Aaron Bunsen Lerner (1920-2007) (Figures 1-3). Although these three dermatologists failed to win the Nobel Prize, it remains a signal accomplishment for each of them to have been nominated for such a prestigious award on multiple occasions in recognition of their outstanding discoveries that have had a significant impact on modern-day medicine. This Fun Facts About Dermatology presentation highlights the lives and careers of Neisser, Hoffmann, and Lerner and the important scientific contributions that led to their nominations for medicine's most coveted award: the Nobel Prize.

摘要

在过去的125年里,有三位皮肤科医生获得了诺贝尔生理学或医学奖提名:阿尔伯特·奈瑟(1855 - 1916)、埃里希·霍夫曼(1868 - 1959)和亚伦·B·勒纳(1920 - 2007)。奈瑟因发现淋球菌以及通过补体结合进行梅毒血清学检测的工作而被提名22次。霍夫曼因在发现梅毒螺旋体方面的作用而被提名三次。勒纳被提名两次,一次是因为他在促黑素细胞激素方面的工作,另一次是因为他在褪黑素方面的工作。尽管奈瑟、霍夫曼和勒纳都没有获得诺贝尔奖,但他们每个人都多次获得这一 prestigious奖项的提名,这仍然是一项值得注意的成就。这一贡献突出了这三位杰出皮肤科医生的生活和职业生涯,包括他们做出的具有里程碑意义的发现,这些发现导致他们获得诺贝尔奖提名。截至2023年,有114项诺贝尔生理学或医学奖授予了227个人,其中没有一位是皮肤科医生。然而,有三位杰出的皮肤科医生获得了这一 illustrious奖项的提名:阿尔伯特·奈瑟(1855 - 1916)、埃里希·霍夫曼(1868 - 1959)和亚伦·本森·勒纳(1920 - 2007)(图1 - 3)。尽管这三位皮肤科医生未能获得诺贝尔奖,但他们每个人都多次获得如此 prestigious奖项的提名,以表彰他们对现代医学产生重大影响的杰出发现,这仍然是一项重大成就。这个关于皮肤科的趣味事实展示突出了奈瑟、霍夫曼和勒纳的生活和职业生涯,以及导致他们获得医学最令人垂涎的奖项——诺贝尔奖提名的重要科学贡献。

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