State Key Laboratory of Swine and Poultry Breeding Industry, Guangzhou, Guangdong, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou 510642, China.
State Key Laboratory of Swine and Poultry Breeding Industry, Guangzhou, Guangdong, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou 510642, China.
J Proteomics. 2024 Sep 30;308:105281. doi: 10.1016/j.jprot.2024.105281. Epub 2024 Aug 21.
Chicken proteomics is a valuable method for comprehending the many mechanisms involved in follicle growth and reproduction in birds. This study offers a thorough summary of the latest progress in chicken proteomics research, specifically highlighting the knowledge obtained regarding follicle development and reproductive physiology. Proteomic studies have revealed essential proteins and pathways that play a role in follicle development, including those that control oocyte size, maturation, and ovulation. Proteomic investigations have provided insight into the molecular pathways that govern reproductive processes. By utilizing advanced proteomic technologies, including mass spectrometry and protein microarray analysis, we have been able to identify and measure many proteins in chicken follicles at their different developmental stages. The utilization of proteomic methods has enabled the identification of previously unknown biomarkers for reproductive efficiency that expedited the creation of innovative diagnostic instruments for monitoring reproductive health in chicken. Chicken proteomics not only offers insights into follicle growth and reproduction but also uncovers the effects of environmental influences on reproductive function. This provides new opportunities for exploring the molecular pathways that cause these effects. The integration of current data with upcoming proteomic technologies offers the potential for innovative strategies to enhance chicken reproduction.
鸡蛋白质组学是理解鸟类卵泡生长和繁殖中涉及的多种机制的一种有价值的方法。本研究全面总结了鸡蛋白质组学研究的最新进展，特别是突出了在卵泡发育和生殖生理学方面获得的知识。蛋白质组学研究揭示了在卵泡发育中起作用的重要蛋白质和途径，包括控制卵母细胞大小、成熟和排卵的途径。蛋白质组学研究为调控生殖过程的分子途径提供了深入了解。通过利用先进的蛋白质组学技术，包括质谱和蛋白质微阵列分析，我们已经能够在鸡卵泡的不同发育阶段鉴定和测量许多蛋白质。蛋白质组学方法的应用使得能够鉴定以前未知的与繁殖效率相关的生物标志物，从而加速了用于监测鸡生殖健康的创新诊断仪器的研发。鸡蛋白质组学不仅提供了对卵泡生长和繁殖的深入了解，还揭示了环境影响对生殖功能的影响。这为探索导致这些影响的分子途径提供了新的机会。将现有数据与即将出现的蛋白质组学技术相结合，为增强鸡繁殖提供了创新策略的潜力。
