神经退行性相关脑重塑的 mRNA 特征的进化观点。
Evolutionary perspectives on mRNA signatures of neurodegeneration-related brain remodelling.
机构信息
Department of Neurology, Penn Frontotemporal Degeneration Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
出版信息
Brain. 2024 Sep 3;147(9):2906-2908. doi: 10.1093/brain/awae267.
Abstract
This scientific commentary refers to ‘Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes’ by Pasquini (https://doi.org/10.1093/brain/awae205).
摘要
这篇科学评论提到了 Pasquini 的“额颞叶变性靶向与最近进化基因表达相关的大脑区域”一文（https://doi.org/10.1093/brain/awae205）。
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本文引用的文献
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Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes.额颞叶变性靶向与最近进化基因表达相关的大脑区域。
Brain. 2024 Sep 3;147(9):3032-3047. doi: 10.1093/brain/awae205.
2
Frontotemporal lobar degeneration.额颞叶变性。
Nat Rev Dis Primers. 2023 Aug 10;9(1):40. doi: 10.1038/s41572-023-00447-0.
3
Genes associated with cognitive ability and HAR show overlapping expression patterns in human cortical neuron types.与认知能力和 HAR 相关的基因在人类皮质神经元类型中表现出重叠的表达模式。
Nat Commun. 2023 Jul 13;14(1):4188. doi: 10.1038/s41467-023-39946-9.
4
Evolutionary and genomic perspectives of brain aging and neurodegenerative diseases.大脑衰老和神经退行性疾病的进化和基因组观点。
Prog Brain Res. 2023;275:165-215. doi: 10.1016/bs.pbr.2022.10.004. Epub 2023 Feb 3.
5
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Biol Psychiatry. 2023 Mar 1;93(5):391-404. doi: 10.1016/j.biopsych.2022.10.016. Epub 2022 Nov 5.
6
Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions.人类加速区对人类神经发育基因调控程序的重编。
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7
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J Neurosci Methods. 2021 May 1;355:109128. doi: 10.1016/j.jneumeth.2021.109128. Epub 2021 Mar 17.
8
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10
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