Kato H, Hiraoka M, Nakajima T, Ishida T
Int J Hyperthermia. 1985 Jan-Mar;1(1):15-28. doi: 10.3109/02656738509029271.
An RF capacitive heating device was constructed and its deep-heating characteristics were studied using three mini-pigs. The deep-heating ability of RF capacitive heating was found to be improved by enlarging the electrodes, driving at 8 MHz, cooling the skin under the electrodes, inserting a bolus between the body and the electrodes and considering the anatomical structure of the body. The heating characteristics obtained were as follows. When applicators were placed on both sides of the abdomen of a mini-pig, 7 mm in fat layer thickness and 23 cm in lateral chest thickness, the increase in temperature of the deep part was greater than that of the fat layer. When applicators were placed on the posterior and anterior abdomen, overheating was noted in the fat and muscle near the back. The temperature was highest in a mock tumour, made by blocking blood flow to the spleen. The bio-heat equation revealed that RF capacitive heating accompanied by surface cooling at 10 degrees C could heat the deep portion of the body to 42 degrees C without excessive heating of a 1.6 cm thick fat layer.
构建了一种射频电容式加热装置，并使用三只小型猪研究了其深部加热特性。研究发现，通过增大电极尺寸、以8 MHz驱动、冷却电极下方的皮肤、在身体与电极之间插入一团物质并考虑身体的解剖结构，可以提高射频电容式加热的深部加热能力。获得的加热特性如下。当将施加器放置在脂肪层厚度为7 mm、侧胸厚度为23 cm的小型猪腹部两侧时，深部温度的升高大于脂肪层。当将施加器放置在腹部前后时，背部附近的脂肪和肌肉出现过热现象。在通过阻断脾脏血流形成的模拟肿瘤中温度最高。生物热方程表明，在10℃表面冷却的情况下，射频电容式加热可以将身体深部加热到42℃，而不会使1.6 cm厚的脂肪层过度受热。
