Université Joseph Ki Zerbo/Institut Supérieur des Sciences de la Population (UJKZ/ISSP), Blvd Charles De Gaulle, 03 BP 7118, Ouagadougou, Burkina Faso.
Institut National de la Statistique et de la Démographie (INSD), 8F4V+443, Av. Pascal Zagré, Ouaga 2000, Ouagadougou, Burkina Faso.
Popul Health Metr. 2024 Aug 18;22(1):21. doi: 10.1186/s12963-024-00341-1.
In malaria-endemic countries, asymptomatic carriers of plasmodium represent an important reservoir for malaria transmission. Estimating the burden at a fine scale and identifying areas at high risk of asymptomatic carriage are important to guide malaria control strategies. This study aimed to estimate the prevalence of asymptomatic carriage at the communal level in Burkina Faso, the smallest geographical entity from which a local development policy can be driven.
The data used in this study came from several open sources: the 2018 Multiple Indicator Cluster Survey on Malaria and the 2019 general census of the population data and environmental. The analysis involved a total of 5489 children under 5 from the malaria survey and 293,715 children under 5 from the census. The Elbers Langjouw and Langjouw (ELL) approach is used to estimate the prevalence. This approach consists of including data from several sources (mainly census and survey data) in a statistical model to obtain predictive indicators at a sub-geographical level, which are not measured in the population census. The method achieves this by finding correlations between common census variables and survey data.
The findings suggest that the spatial distribution of the prevalence of asymptomatic carriage is very heterogeneous across the communes. It varies from a minimum of 5.1% (95% CI 3.6-6.5) in the commune of Bobo-Dioulasso to a maximum of 41.4% (95% CI 33.5-49.4) in the commune of Djigoué. Of the 341 communes, 208 (61%) had prevalences above the national average of 20.3% (95% CI 18.8-21.2).
This analysis provided commune-level estimates of the prevalence of asymptomatic carriage of plasmodium in Burkina Faso. The results of this analysis should help to improve planning of malaria control at the communal level in Burkina Faso.
在疟疾流行的国家，无症状疟原虫携带者是疟疾传播的重要传染源。在精细尺度上估计负担，并确定高无症状携带风险的地区，对于指导疟疾控制策略非常重要。本研究旨在估计布基纳法索社区层面无症状携带的流行率，这是可以驱动地方发展政策的最小地理实体。
本研究使用的数据来自多个公开来源：2018 年疟疾多指标类集调查和 2019 年人口数据和环境普查。分析共涉及疟疾调查中的 5489 名 5 岁以下儿童和普查中的 293715 名 5 岁以下儿童。使用 Elbers Langjouw 和 Langjouw（ELL）方法来估计流行率。该方法包括将多个来源的数据（主要是普查和调查数据）纳入统计模型，以获得亚地理水平的预测指标，这些指标在人口普查中未被测量。该方法通过找到常见普查变量与调查数据之间的相关性来实现这一点。
结果表明，无症状携带的流行率在各社区之间的空间分布非常不均匀。从博博迪乌拉索社区的最低 5.1%（95%CI 3.6-6.5）到吉古社区的最高 41.4%（95%CI 33.5-49.4）不等。在 341 个社区中，208 个（61%）的流行率高于全国平均水平 20.3%（95%CI 18.8-21.2）。
本分析提供了布基纳法索社区层面无症状携带疟原虫流行率的估计。该分析的结果应该有助于改善布基纳法索社区层面的疟疾控制规划。
