Jaraiz Magariños Irene, Martínez Alicia F, Satué de Velasco Eduardo, Agustín Eduardo, Allué José Luis, López Silvia
Farmacéutica comunitaria en Avilés (Principado de Asturias) España.
Farmacéutica comunitaria en La Caridad (Principado de Asturias). España.
Farm Comunitarios. 2023 Mar 17;15(2):5-11. doi: 10.33620/FC.2173-9218.(2023).10. eCollection 2023 Apr 14.
Some preliminary studies that reveal the onset of risk factors not investigated previously in regard to the health system were performed. They can reduce adherence and/or persistence of pharmacological treatments. Knowledge about them can lead to possible solutions.
To estimate the incidence of risk factors in regard to the health system that can reduce adherence/persistence with treatments associated with problems accessing these in the community pharmacy.
Transversal, randomized, prospective study in community pharmacies in Asturias and Aragón regions. The primary endpoint was the incidence of new risk factors that means that the prescription is inadequate for its dispensing. Different subgroups were analyzed according to type of risk factor, population and prescription.
The typical patient is a vulnerable person according to his age (65.4 years), multipathology and polypharmacy (6.8 drugs). After the evaluation of 138,697 cases of dispensing in 98 community pharmacies a total of 2009 patients were detected with 2221 cases of dispensing with risk factors in terms of adherence and/or persistence (1.6% of the total dispensing). The type of incidence most commonly observed was expiry of the prescription (54.7%; 95%CI=52.6-56.8), followed by no prescription record (18.7%; 95%CI: 17.1-20.3). For its part supply problems stood at 10.2% (95%CI= 10.6%-10.9%). The most compromised therapeutic groups were groups N Nervous System (27.6%), C Cardiovascular System (20.3%) and A Gastrointestinal System (15.3%).
The results obtained suggest that the current incidence of risk factors in regard to the health system in terms of adherence and/or persistence may comprise a health problem with a clinical, quality of life and financial impact. As these risk factors are modifiable, a greater capacity for community pharmaceutical action by means of exceptional dispensing to authorize the treatment's continuity would be an acceptable solution.
开展了一些初步研究，揭示了此前未针对卫生系统进行调查的风险因素的出现情况。这些因素会降低药物治疗的依从性和/或持续性。了解这些因素有助于找到可能的解决办法。
评估卫生系统中可能降低社区药房与获取治疗相关问题的治疗依从性/持续性的风险因素的发生率。
在阿斯图里亚斯和阿拉贡地区的社区药房开展横向、随机、前瞻性研究。主要终点是新风险因素的发生率，即处方不适合配药的情况。根据风险因素类型、人群和处方对不同亚组进行分析。
典型患者根据年龄（65.4岁）、多种病理状况和多种药物治疗（6.8种药物）属于弱势群体。在对98家社区药房的138,697例配药情况进行评估后，共检测到2009例患者存在2221例在依从性和/或持续性方面存在风险因素的配药情况（占总配药的1.6%）。最常观察到的发生率类型是处方过期（54.7%；95%置信区间=52.6 - 56.8），其次是无处方记录（18.7%；95%置信区间：17.1 - 20.3）。供应问题占10.2%（95%置信区间=10.6% - 10.9%）。受影响最大的治疗组是N神经系统组（27.6%）、C心血管系统组（20.3%）和A胃肠道系统组（15.3%）。
所获得的结果表明，目前卫生系统中在依从性和/或持续性方面的风险因素发生率可能构成一个具有临床、生活质量和经济影响的健康问题。由于这些风险因素是可改变的，通过特殊配药以授权治疗连续性的方式提高社区药学行动能力将是一个可接受的解决方案。
