Yang Ni, Liu Zhen, Jin Tong, Xin Hai-Wei, Gu Li, Zheng Yue, Zhou Hui-Xing, Li Ning, Liu Xin-Juan
Department of Gastroenterology, Beijing Chao-Yang Hospital, Capital University of Medical Science, Beijing 100020, China.
Department of Infectious Diseases and Clinical Microbiology, Beijing Chao-Yang Hospital, Capital University of Medical Science, Beijing 100020, China.
World J Gastrointest Endosc. 2024 Aug 16;16(8):483-488. doi: 10.4253/wjge.v16.i8.483.
Multisystem inflammatory syndrome in adults (MIS-A) is a rare but severe disease occurring several weeks after severe acute respiratory syndrome coronavirus 2 infection. It develops in adults with inflammation of different organs including the gastrointestinal tract, heart, kidneys, skin and hematopoietic system.
We present a 58-year-old Chinese man diagnosed with MIS-A. His chief complaints were fever, generalized fatigue and anorexia, accompanied with rashes on his back. Further examination showed cardiac, renal and liver injury. He had melena and gastroscopy indicated esophageal ulcer and severe esophagitis. Repeated blood and sputum culture did not show growth of bacteria or fungi. Antibiotic treatment was stopped due to unsatisfactory performance. His condition improved after prednisone and other supportive treatment.
Gastrointestinal involvement in MIS-A is not uncommon. Intestinal involvement predominates, and esophageal involvement is rarely reported. Esophageal ulcer with bleeding could also be a manifestation of MIS-A.
成人多系统炎症综合征（MIS-A）是一种罕见但严重的疾病，发生在严重急性呼吸综合征冠状病毒2感染数周后。它在成人中发病，伴有包括胃肠道、心脏、肾脏、皮肤和造血系统在内的不同器官的炎症。
我们报告一名58岁的中国男性被诊断为MIS-A。他的主要症状为发热、全身乏力和厌食，伴有背部皮疹。进一步检查显示心脏、肾脏和肝脏损伤。他有黑便，胃镜检查显示食管溃疡和严重食管炎。多次血培养和痰培养未发现细菌或真菌生长。由于治疗效果不佳，停用了抗生素。在泼尼松和其他支持治疗后，他的病情有所改善。
MIS-A累及胃肠道并不罕见。以肠道受累为主，食管受累报道较少。伴有出血的食管溃疡也可能是MIS-A的一种表现。
