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[新冠疫情期间苯二氮䓬类药物使用者的药物干预措施]

[Pharmaceutical Interventions in Benzodiazepine users during the COVID-19 Pandemic].

作者信息

Alberto-Armas Daida, Rubio-Armendáriz Carmen, Hernández-García Verónica, Santana-Ayala Juan Ramón, Hardisson-de-la-Torre Arturo, Román-Castillo Yanira

机构信息

Doctora en Ciencias Médicas y Farmacéuticas, Desarrollo y Calidad de Vida. Área de Toxicología. Universidad de La Laguna. Farmacéutica Comunitaria en San Cristóbal de La Laguna. Universidad de La Laguna España.

Catedrática de Toxicología. Profesora Titular del Área de Toxicología de la Universidad de La Laguna Universidad de La Laguna España.

出版信息

Farm Comunitarios. 2024 Feb 26;16(2):29-36. doi: 10.33620/FC.2173-9218.(2024).09. eCollection 2024 Apr 15.

DOI:10.33620/FC.2173-9218.(2024).09
PMID:39156032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11329726/
Abstract

INTRODUCTION

Pharmaceutical Intervention aims to optimize and rationalize the use, effectiveness, and safety of dispensed medications resolving drug-related problems (DRPs) and negative medicine outcomes (NMOs).

OBJECTIVES

To evaluate Pharmaceutical Interventions in Benzodiazepines users during the COVID-19 pandemic from a Community Pharmacy.

METHOD

Prospective observational, descriptive, and cross-sectional study (AEMPS code: DAA-CLO-2020-01) of Pharmaceutical Interventions offered by the community pharmacy between August 2020 and February 2021.

RESULTS

A total of 306 Pharmaceutical Interventions were conducted involving 127 patients. Health education and personalized medication information were the most common Pharmaceutical Interventions after detecting a high level of unfamiliarity with the Benzodiazepines among patients. Pharmaceutical Interventions leading to medical referrals accounted for 37.8% of the total, triggered by the detection of DRPs and/or NMOs or after identifying the patient as candidate for deprescription. These referrals included patients with a very high level of depression according to the Euroqol 5D-3L test. Pharmaceutical Interventions resulting in Medication Review with Follow-up Service were performed in 3.1% of patients. The patient acceptance rate of Pharmaceutical Interventions reached 98.4%.

CONCLUSIONS

The high acceptance rate of Pharmaceutical Interventions reinforces the value of Community Pharmacy in optimizing and rationalizing Benzodiazepines usage, while strengthening the pharmacist-patient relationship. The COVID-19 pandemic posed challenges to pharmacist-physician collaboration despite of the availability of telecommunication protocols among healthcare professionals.

摘要

引言

药物干预旨在优化和合理使用已配发药物，提高其有效性和安全性，解决药物相关问题（DRP）和负面药物结果（NMO）。

目的

从社区药房评估新冠疫情期间苯二氮䓬类药物使用者的药物干预情况。

方法

对2020年8月至2021年2月社区药房提供的药物干预进行前瞻性观察、描述性和横断面研究（西班牙药品和医疗器械管理局代码：DAA-CLO-2020-01）。

结果

共进行了306次药物干预，涉及127名患者。在发现患者对苯二氮䓬类药物的熟悉程度较低后，健康教育和个性化用药信息是最常见的药物干预措施。因发现药物相关问题和/或负面药物结果或确定患者为减药候选者而导致的医疗转诊占总数的37.8%。这些转诊包括根据欧洲五维健康量表5D-3L测试显示抑郁程度非常高的患者。3.1%的患者接受了药物审查及后续服务的药物干预。药物干预的患者接受率达到98.4%。

结论

药物干预较高的接受率强化了社区药房在优化和合理使用苯二氮䓬类药物方面的价值，同时加强了药师与患者的关系。尽管医疗专业人员之间有电信协议，但新冠疫情给药师与医生的合作带来了挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf6c/11329726/5013bea966b6/FC16-02-04_gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf6c/11329726/5805b7ed7643/FC16-02-04_gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf6c/11329726/5013bea966b6/FC16-02-04_gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf6c/11329726/5805b7ed7643/FC16-02-04_gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf6c/11329726/5013bea966b6/FC16-02-04_gf02.jpg

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