Gavilán-Moral Enrique, Villafaina-Barroso Antonio, Jiménez-de Gracia Laura, Gómez Santana María del Carmen
Servicio de Medicina de Familia, Laboratorio de Prácticas Innovadoras en Polimedicación y Salud, polimedicado.com, Plasencia, España.
Rev Esp Geriatr Gerontol. 2012 Jul-Aug;47(4):162-7. doi: 10.1016/j.regg.2012.01.003. Epub 2012 Jun 8.
Deprescribing is the process of reconstructing multiple medication use by review and analysis and which concludes with dose modification, replacement or elimination of some drugs or adding others. Its development is intended to resolve tensions and contradictions between two sets of questions: 1/is life expectancy shorter than the time the drug takes to obtain a benefit?, and 2/are the goals of prescribing-deprescribing consistent with those of care? The validity of the rationale on deprescribing is based on scientific and ethical reasons. The usefulness and safety of many drugs that frail elderly or terminally ill takes is unknown, and other drugs may cause troublesome or severe side effects. Thus, in some cases their removal could be justified, being substantially safe doing so.
减药是通过审查和分析来重构多种药物使用情况的过程，其结果是对某些药物进行剂量调整、替换或停用，或添加其他药物。其发展旨在解决两组问题之间的紧张关系和矛盾：1.预期寿命是否短于药物获得益处所需的时间？2.开药-减药的目标是否与护理目标一致？减药理论依据的有效性基于科学和伦理原因。体弱的老年人或绝症患者服用的许多药物的有效性和安全性尚不清楚，其他药物可能会引起麻烦或严重的副作用。因此，在某些情况下，停用这些药物可能是合理的，而且这样做基本安全。
