Sinha Yash, Bhattacharjee Debangana, Pradhan Prasanti, Tilokani Akansha, Banka Aanchal
Department of Conservative Dentistry and Endodontics, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology (KIIT) Deemed to be University, Bhubaneswar, IND.
Cureus. 2024 Jul 18;16(7):e64796. doi: 10.7759/cureus.64796. eCollection 2024 Jul.
This case report explores the application of platelet-rich fibrin (PRF) as an autologous biomaterial in the surgical management of a periapical cyst in an 18-year-old female patient. The patient presented with pain, discoloration, and swelling in the maxillary left central incisor region, indicative of an asymptomatic periapical lesion associated with a history of trauma. Despite initial endodontic treatment with calcium hydroxide, the lesion persisted, necessitating surgical intervention. PRF, prepared from the patient's blood, was utilized during periapical surgery to promote healing and tissue regeneration. The surgical procedure included enucleation of the cyst, apicoectomy, and retrograde filling with Biodentine. Clinical and radiographic assessments at follow-up visits (three, six, and nine months post-surgery) revealed successful healing with no signs of inflammation or discomfort. The use of PRF demonstrated favorable outcomes in enhancing wound healing and maintaining a favorable environment for tissue remodeling. This case underscores the potential of PRF as an effective biomaterial in periapical surgery, advocating for its integration into dental therapeutic strategies for its regenerative properties and cost-effectiveness.
本病例报告探讨了富血小板纤维蛋白（PRF）作为一种自体生物材料在一名18岁女性患者根尖周囊肿手术治疗中的应用。患者上颌左中切牙区域出现疼痛、变色和肿胀，提示存在与外伤史相关的无症状根尖周病变。尽管最初用氢氧化钙进行了根管治疗，但病变仍持续存在，需要进行手术干预。在根尖周手术中使用了从患者血液中制备的PRF，以促进愈合和组织再生。手术过程包括囊肿摘除术、根尖切除术以及用BioDentine进行倒充填。随访（术后三个月、六个月和九个月）时的临床和影像学评估显示愈合成功，无炎症或不适迹象。PRF的使用在促进伤口愈合和维持有利于组织重塑的环境方面显示出良好效果。该病例强调了PRF作为根尖周手术中一种有效生物材料的潜力，因其再生特性和成本效益，主张将其纳入牙科治疗策略。
