Frank F, Fabrizi A P, Frank-Ricci R, Sturiale C, Nuzzo G
Appl Neurophysiol. 1985;48(1-6):121-6. doi: 10.1159/000101115.
The authors report their results of 37 patients with low malignancy brain tumors seated in deep or highly functional areas not amenable to traditional surgery, nor to conventional radiochemotherapy. In the past 5 years these patients were treated by means of stereotactic interstitial radiotherapy. The isotope employed in all cases was 125I. Stereotactic radioisotope implants were always preceded by multiple stereotactic biopsies affording precise histological diagnoses. A 6-month to 5-year follow-up shows a survival rate of 72.6% (29 patients), and of these patients, 80.9% (26 out of 29) had complete social reentry.
作者报告了37例低恶性脑肿瘤患者的治疗结果，这些肿瘤位于深部或功能高度区，无法进行传统手术，也无法进行常规放化疗。在过去5年中，这些患者接受了立体定向间质放射治疗。所有病例均采用125I同位素。立体定向放射性同位素植入前均进行多次立体定向活检以提供精确的组织学诊断。6个月至5年的随访显示生存率为72.6%（29例患者），其中80.9%（29例中的26例）已完全重新融入社会。
