School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
Shanghai Xirong Information Science and Technology Co., Ltd., National Science and Technology Park, Tongji University, Shanghai 200092, China.
World J Gastroenterol. 2024 Aug 7;30(29):3456-3460. doi: 10.3748/wjg.v30.i29.3456.
Non-alcoholic fatty liver disease (NAFLD) is characterized by symptoms of excessive fat accumulation and steatosis in the liver without alcohol intake in patients. The associated pathogenic mechanism is not completely understood and there are no specific drugs for patients with NAFLD. Exercise and diet adherence are the best options for the management of NAFLD patients. Questionnaire associated analysis models of adherence to these interventions are used to assess their effectiveness in the management of NAFLD patients using specificity, sensitivity, and so on. Studies have indicated that the relative ratio of NAFLD can be reduced by physical activity with diet control. In the future, the pathogenesis of NAFLD should be clarified with stratified efforts to develop appropriate drugs, and both exercise and diet adherence should be optimized using better questionnaire design and evaluation models for patients with NAFLD.
非酒精性脂肪性肝病(NAFLD)的特征是患者肝脏内脂肪蓄积和脂肪变性的症状,而无酒精摄入。相关的发病机制尚不完全清楚,也没有针对 NAFLD 患者的特定药物。运动和饮食依从性是 NAFLD 患者管理的最佳选择。使用特定性、敏感性等,通过问卷相关分析模型来评估这些干预措施对 NAFLD 患者管理的有效性。研究表明,通过饮食控制和体育锻炼可以降低 NAFLD 的相对比值。未来应通过分层努力阐明 NAFLD 的发病机制,开发合适的药物,同时优化运动和饮食依从性,为 NAFLD 患者设计更好的问卷和评估模型。