Petersen Johannes, Böning Henrike, Yildirim Sevenai, Alassar Yousuf, Yildirim Yalin, Bazhanov Ilia, Sinning Christoph, Reichenspurner Hermann, Pecha Simon
Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany.
JTCVS Tech. 2024 May 23;26:43-49. doi: 10.1016/j.xjtc.2024.05.007. eCollection 2024 Aug.
Closure of the left atrial appendage (LAA) is a routine part of atrial fibrillation ablation surgery and significantly reduces stroke rates. Different LAA-closure techniques are used in cardiac surgery with variable results reported. We therefore evaluated the efficacy of 4 different LAA-closure techniques in patients undergoing cardiac surgery.
In total, 149 patients who underwent concomitant LAA closure during cardiac surgery between 2015 and 2019 were included in this retrospective transesophageal echocardiography study. Four different LAA-closure techniques were evaluated: LAA clipping (n = 62), suture ligation (n = 28), stapler resection (n = 30), and surgical LAA excision (n = 29). Successful LAA closure was defined as absence of LAA perfusion and absence of a stump greater than 10 mm.
The mean patients age was 68.7 ± 9.4 years; 61.7% were male. No complications related to LAA closure were observed. Mean follow-up was 36.5 ± 8 months. Transesophageal echocardiography follow-up showed the following LAA closure success rates: LAA clip 98.4%, surgical excision 93.1%, stapler resection 76.6%, and suture ligation 39.2%. Suture ligation resulted in a high rate of recanalization (50%) and residual stumps (10.8%), whereas stapler resection resulted in a high rate of residual stumps (23.4%). Overall, 4 patients (2.7%) had a stroke during follow-up. In detail, 2 of 27 (7.4%) patients with unsuccessful LAA closure had a stroke, whereas 2 of the 122 (1.6%) patients with successful LAA closure had a stroke.
In our study, LAA clipping and surgical LAA excision proved to be both successful LAA-closure methods. External LAA ligation and stapler resection resulted in low rates of successful LAA closure and should be avoided.
左心耳(LAA)封堵是房颤消融手术的常规组成部分,可显著降低卒中发生率。心脏手术中使用了不同的LAA封堵技术,报道的结果各不相同。因此,我们评估了4种不同LAA封堵技术在接受心脏手术患者中的疗效。
本项回顾性经食管超声心动图研究纳入了2015年至2019年间在心脏手术期间同时进行LAA封堵的149例患者。评估了4种不同的LAA封堵技术:LAA夹闭术(n = 62)、缝合结扎术(n = 28)、吻合器切除术(n = 30)和外科LAA切除术(n = 29)。成功的LAA封堵定义为LAA无血流灌注且残端长度不超过10 mm。
患者平均年龄为68.7±9.4岁;61.7%为男性。未观察到与LAA封堵相关的并发症。平均随访时间为36.5±8个月。经食管超声心动图随访显示LAA封堵成功率如下:LAA夹闭术98.4%,外科切除术93.1%,吻合器切除术76.6%,缝合结扎术39.2%。缝合结扎术导致再通率高(50%)和残端残留率高(10.8%),而吻合器切除术导致残端残留率高(23.4%)。总体而言,4例患者(2.7%)在随访期间发生卒中。具体而言,27例LAA封堵失败的患者中有2例(7.4%)发生卒中,而122例LAA封堵成功的患者中有2例(占1.6%)发生卒中。
在我们的研究中,LAA夹闭术和外科LAA切除术被证明都是成功的LAA封堵方法。外部LAA结扎术和吻合器切除术导致LAA封堵成功率较低,应避免使用。