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初次和翻修全髋关节置换术中双动式植入物:一项系统评价和荟萃分析。

Dual-mobility implants in primary and revision total hip arthroplasty: A systematic review and meta-analysis.

作者信息

Saroha Sarup, Raheman Firas J, Jaiswal Parag K, Patel Akash

机构信息

University College London, London, United Kingdom.

Royal Free London NHS Foundation Trust, London, United Kingdom.

出版信息

J Clin Orthop Trauma. 2024 Jul 18;54:102495. doi: 10.1016/j.jcot.2024.102495. eCollection 2024 Jul.

Abstract

PURPOSE

Total hip arthroplasty (THA) is a common and successful operation. However, dislocation remains a significant cause of implant failure in fixed-bearing designs. This study investigated the effect of dual-mobility implants (DM) compared to fixed-bearing (FB) implants on all-cause revisions, revisions due to dislocation, post-operative complications and functional scores in patients undergoing primary and revision THA.

METHODS

A systematic review was performed including studies that compared DM with FB implants in primary or revision THA according to PRISMA guidelines, and was registered in PROSPERO (ID CRD42023403736). The Cochrane Library, Embase, MEDLINE, Web of Science, and Scopus were searched from the time of database inception to March 12, 2023. Eligible studies underwent meta-analysis and risk of bias assessment using the ROBINS-I tool. Treatment effects were assessed using odds ratios and data were pooled using a random-effects maximum-likelihood, where appropriate.

RESULTS

Eight comparative, non-randomised studies involving 2810 DM implants and 3188 FB implants were included. In primary THA, there was an imprecise estimate of the difference in all-cause revision (OR 0.82, 95 % CI 0.25-2.72) and a significant benefit for the DM cohort in revision due to dislocation (OR 0.08, 95 % CI 0.02-0.28). In revision THA, the DM cohort showed benefit in all-cause revision (OR 0.57, 95 % CI 0.31-1.05) and revision due to dislocation (OR 0.14, 95 % CI 0.04-0.53). DM implants were associated with a lower incidence of implant dislocation and infection. The analysis of functional outcomes was limited due to reporting limitations. No intraprosthetic dislocations were observed.

CONCLUSION

The results suggest that contemporary DM designs may be advantageous in reducing the risk of all-cause revision, revision due to dislocation, and post-operative complication incidence at mid-term follow-up. Further high-quality prospective studies are needed to evaluate the long-term risk profile of this design, especially in the revision context.

摘要

目的

全髋关节置换术(THA)是一种常见且成功的手术。然而,在固定承重设计中,脱位仍然是植入物失败的一个重要原因。本研究调查了双动式植入物(DM)与固定承重(FB)植入物相比,对初次和翻修THA患者的全因翻修、因脱位导致的翻修、术后并发症及功能评分的影响。

方法

根据PRISMA指南进行系统评价,纳入比较DM与FB植入物用于初次或翻修THA的研究,并在PROSPERO(ID CRD42023403736)注册。从数据库建立至2023年3月12日,检索了Cochrane图书馆、Embase、MEDLINE、Web of Science和Scopus。对符合条件的研究使用ROBINS-I工具进行荟萃分析和偏倚风险评估。使用比值比评估治疗效果,并在适当情况下采用随机效应最大似然法汇总数据。

结果

纳入八项比较性、非随机研究,涉及2810个DM植入物和3188个FB植入物。在初次THA中,全因翻修差异估计不精确(比值比0.82,95%可信区间0.25-2.72),DM组在因脱位导致的翻修方面有显著益处(比值比0.08,95%可信区间0.02-0.28)。在翻修THA中,DM组在全因翻修(比值比0.57,95%可信区间0.31-1.05)和因脱位导致的翻修(比值比0.14,95%可信区间0.04-0.53)方面显示出益处。DM植入物与较低的植入物脱位和感染发生率相关。由于报告限制,功能结局分析有限。未观察到假体内部脱位。

结论

结果表明,当代DM设计在中期随访中可能有利于降低全因翻修、因脱位导致的翻修及术后并发症发生率的风险。需要进一步开展高质量的前瞻性研究,以评估该设计的长期风险状况,尤其是在翻修情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/257c/11324850/8d728d87c7e6/gr1.jpg

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