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Monitoring of molecular responses to tirabrutinib in a cohort of exceptional responders with relapsed/refractory mantle cell lymphoma.

作者信息

Alqahtani Abdullah N M, Jayne Sandrine, Ahearne Matthew J, Trethewey Christopher S, Duraisingham Sai S, Lehmann Susann, Cowley Caroline M, Dyer Martin J S, Walter Harriet S

机构信息

The Ernest and Helen Scott Haematological Research Institute, Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester Leicester UK.

Department of Haematology University Hospitals Leicester Leicester UK.

出版信息

EJHaem. 2024 Jun 24;5(4):896-899. doi: 10.1002/jha2.966. eCollection 2024 Aug.

DOI:10.1002/jha2.966
PMID:39157626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11327755/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/206e/11327755/2a1865e02420/JHA2-5-896-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/206e/11327755/2a1865e02420/JHA2-5-896-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/206e/11327755/2a1865e02420/JHA2-5-896-g001.jpg

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CD5 Gene Signature Identifies Diffuse Large B-Cell Lymphomas Sensitive to Bruton's Tyrosine Kinase Inhibition.CD5 基因标志物可识别对布鲁顿酪氨酸激酶抑制敏感的弥漫性大 B 细胞淋巴瘤。
J Clin Oncol. 2024 Feb 1;42(4):467-480. doi: 10.1200/JCO.23.01574. Epub 2023 Dec 11.
2
Long-term Outcomes With Ibrutinib Treatment for Patients With Relapsed/Refractory Mantle Cell Lymphoma: A Pooled Analysis of 3 Clinical Trials With Nearly 10 Years of Follow-up.依鲁替尼治疗复发/难治性套细胞淋巴瘤患者的长期结局:三项临床试验近10年随访的汇总分析
Hemasphere. 2022 Apr 13;6(5):e712. doi: 10.1097/HS9.0000000000000712. eCollection 2022 May.
3
Zanubrutinib in relapsed/refractory mantle cell lymphoma: long-term efficacy and safety results from a phase 2 study.
泽布替尼治疗复发/难治性套细胞淋巴瘤:来自 2 期研究的长期疗效和安全性结果。
Blood. 2022 May 26;139(21):3148-3158. doi: 10.1182/blood.2021014162.
4
Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL.伊布替尼联合 R-CHOP 化疗治疗弥漫性大 B 细胞淋巴瘤的遗传学亚型。
Cancer Cell. 2021 Dec 13;39(12):1643-1653.e3. doi: 10.1016/j.ccell.2021.10.006. Epub 2021 Nov 4.
5
Acalabrutinib for treatment of diffuse large B-cell lymphoma: results from a phase Ib study.阿卡替尼治疗弥漫性大B细胞淋巴瘤:Ib期研究结果
Haematologica. 2021 Oct 1;106(10):2774-2778. doi: 10.3324/haematol.2021.278654.
6
Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment.对治疗表现出异常反应的癌症的分子特征
Cancer Cell. 2021 Jan 11;39(1):38-53.e7. doi: 10.1016/j.ccell.2020.10.015. Epub 2020 Nov 19.
7
Phase I/II study of tirabrutinib, a second-generation Bruton's tyrosine kinase inhibitor, in relapsed/refractory primary central nervous system lymphoma.替拉鲁替尼(第二代布鲁顿酪氨酸激酶抑制剂)治疗复发/难治性原发性中枢神经系统淋巴瘤的 I/II 期研究。
Neuro Oncol. 2021 Jan 30;23(1):122-133. doi: 10.1093/neuonc/noaa145.
8
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Leukemia. 2019 Nov;33(11):2762-2766. doi: 10.1038/s41375-019-0575-9. Epub 2019 Sep 26.