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Long-term Outcomes With Ibrutinib Treatment for Patients With Relapsed/Refractory Mantle Cell Lymphoma: A Pooled Analysis of 3 Clinical Trials With Nearly 10 Years of Follow-up.

作者信息

Dreyling Martin, Goy Andre, Hess Georg, Kahl Brad S, Hernández-Rivas José-Ángel, Schuier Natasha, Qi Keqin, Deshpande Sanjay, Zhu Angeline, Parisi Lori, Wang Michael L

机构信息

Department of Medicine III, University Hospital, Ludwig Maximilians University, Munich, Germany.

Department of Hematology & Oncology, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, USA.

出版信息

Hemasphere. 2022 Apr 13;6(5):e712. doi: 10.1097/HS9.0000000000000712. eCollection 2022 May.

DOI:10.1097/HS9.0000000000000712
PMID:35441128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9010121/
Abstract
摘要

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Long-term Outcomes With Ibrutinib Treatment for Patients With Relapsed/Refractory Mantle Cell Lymphoma: A Pooled Analysis of 3 Clinical Trials With Nearly 10 Years of Follow-up.依鲁替尼治疗复发/难治性套细胞淋巴瘤患者的长期结局:三项临床试验近10年随访的汇总分析
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2
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Blood Neoplasia. 2025 Jun 9;2(3):100128. doi: 10.1016/j.bneo.2025.100128. eCollection 2025 Aug.
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Front Immunol. 2025 Jul 9;16:1620895. doi: 10.3389/fimmu.2025.1620895. eCollection 2025.
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First Line Therapy in Mantle Cell Lymphoma-The Role of BTKi in the Initial Treatment of Transplant-Eligible and -Ineligible Patients.

本文引用的文献

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Outcomes in first relapsed-refractory younger patients with mantle cell lymphoma: results from the MANTLE-FIRST study.初治复发/难治性年轻套细胞淋巴瘤患者的结局:MANTLE-FIRST 研究结果。
Leukemia. 2021 Mar;35(3):787-795. doi: 10.1038/s41375-020-01013-3. Epub 2020 Aug 11.
2
Patterns of survival in patients with recurrent mantle cell lymphoma in the modern era: progressive shortening in response duration and survival after each relapse.现代时代复发性套细胞淋巴瘤患者的生存模式:每次复发后反应持续时间和生存时间逐渐缩短。
Blood Cancer J. 2019 May 20;9(6):50. doi: 10.1038/s41408-019-0209-5.
3
Ibrutinib for the treatment of relapsed/refractory mantle cell lymphoma: extended 3.5-year follow up from a pooled analysis.
套细胞淋巴瘤的一线治疗——BTKi在适合和不适合移植患者初始治疗中的作用
Hematol Oncol. 2025 Jun;43 Suppl 2(Suppl 2):e70073. doi: 10.1002/hon.70073.
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Resistance mechanisms and clonal dynamics in mantle cell lymphoma treated with sequential BTKi and venetoclax therapy.序贯使用布鲁顿酪氨酸激酶抑制剂(BTKi)和维奈克拉治疗套细胞淋巴瘤的耐药机制与克隆动力学
J Pathol. 2025 Aug;266(4-5):395-404. doi: 10.1002/path.6434. Epub 2025 May 15.
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J Clin Oncol. 2025 Jul 10;43(20):2276-2284. doi: 10.1200/JCO-25-00690. Epub 2025 May 1.
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Hematology Am Soc Hematol Educ Program. 2024 Dec 6;2024(1):42-47. doi: 10.1182/hematology.2024000546.
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EJHaem. 2024 Jun 24;5(4):896-899. doi: 10.1002/jha2.966. eCollection 2024 Aug.
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Hemasphere. 2024 Jun 13;8(6):e87. doi: 10.1002/hem3.87. eCollection 2024 Jun.
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J Blood Med. 2024 May 25;15:239-254. doi: 10.2147/JBM.S463946. eCollection 2024.
依鲁替尼治疗复发/难治性套细胞淋巴瘤:汇总分析的3.5年延长随访结果
Haematologica. 2019 May;104(5):e211-e214. doi: 10.3324/haematol.2018.205229. Epub 2018 Nov 15.
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Time to progression of mantle cell lymphoma after high-dose cytarabine-based regimens defines patients risk for death.基于大剂量阿糖胞苷方案的套细胞淋巴瘤进展时间可确定患者的死亡风险。
Br J Haematol. 2019 Jun;185(5):940-944. doi: 10.1111/bjh.15643. Epub 2018 Nov 8.
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Br J Haematol. 2017 Nov;179(3):430-438. doi: 10.1111/bjh.14870. Epub 2017 Aug 18.
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Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study.依鲁替尼对比替西罗莫司治疗复发或难治性套细胞淋巴瘤患者:一项国际性、随机、开放标签、3 期研究。
Lancet. 2016 Feb 20;387(10020):770-8. doi: 10.1016/S0140-6736(15)00667-4. Epub 2015 Dec 7.
8
Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma.伊布替尼治疗复发或难治性套细胞淋巴瘤中的 BTK。
N Engl J Med. 2013 Aug 8;369(6):507-16. doi: 10.1056/NEJMoa1306220. Epub 2013 Jun 19.