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牙髓石及其与代谢性疾病的相关性。

Dental pulp stones and their correlation with metabolic diseases.

作者信息

Khan Mohammad Imran, Khare Abhisheik, Arif Khushboo, Khan Sameera Shamim, Nasir Abdullah, Lari Shafik

机构信息

Department of Oral and Maxillofacial Pathology and Oral Microbiology, Career Post Graduate Institute of Dental Sciences and Hospital, Ghaila, IIM Road Lucknow, Uttar Pradesh, India.

Department of Public Health Dentistry, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.

出版信息

J Oral Maxillofac Pathol. 2024 Apr-Jun;28(2):192-199. doi: 10.4103/jomfp.jomfp_536_23. Epub 2024 Jul 11.

Abstract

BACKGROUND

Dental pulp calcifications or pulp stones are calcified structures found in dental pulp, mostly around or enclosing a blood vessel. The formation of these calcifications begins with concentric layers of calcified tissue within which remnants of necrotic and calcified cells may be present. The calcifications of thrombi in blood vessels, called phleboliths, may also serve as nidi for denticles. In metabolic diseases such as diabetes, hypertension or poor periodontal health, there are obvious changes in blood vessels and vascularization. In our study, we observed histopathological sections of dental pulp and correlated systemic diseases such as diabetes and hypertension with poor periodontal health and dental pulp stones.

AIM

The aim of our study was to evaluate the histopathology of dental pulp stones, their distribution among various age groups and sexes and to identify any correlations between pulp stone formation and systemic diseases such as type II diabetes and hypertension.

MATERIALS AND METHODS

Samples from 100 patients with metabolic diseases such as type II diabetes and hypertension were collected. The pulp was extirpated from the teeth that were undergoing root canal treatment, and the teeth were extracted. The collected pulp sample was fixed in 10% formaline neutral buffer, subjected to routine histopathological procedures and stained with haematoxylin and eosin. The pulp of teeth extracted for orthodontic treatment was considered a control for patients with no metabolic disease.

RESULTS

There was a definite relationship between increased pulp stones and metabolic diseases such as type II diabetes and hypertension; likewise, poor periodontal health was significantly related to pulp stones.

摘要

背景

牙髓钙化或牙髓石是在牙髓中发现的钙化结构,大多围绕或包绕血管。这些钙化的形成始于钙化组织的同心层,其中可能存在坏死和钙化细胞的残余物。血管内血栓的钙化,即静脉石,也可能作为髓石的核心。在糖尿病、高血压等代谢性疾病或牙周健康状况不佳时,血管和血管形成会有明显变化。在我们的研究中,我们观察了牙髓的组织病理学切片,并将糖尿病和高血压等全身性疾病与牙周健康不佳和牙髓石进行了关联。

目的

我们研究的目的是评估牙髓石的组织病理学、它们在不同年龄组和性别中的分布,并确定髓石形成与II型糖尿病和高血压等全身性疾病之间的任何关联。

材料与方法

收集了100例患有II型糖尿病和高血压等代谢性疾病患者的样本。从正在接受根管治疗的牙齿中摘除牙髓,并拔除牙齿。将收集到的牙髓样本固定在10%中性福尔马林缓冲液中,进行常规组织病理学程序,并用苏木精和伊红染色。因正畸治疗而拔除的牙齿的牙髓被视为无代谢疾病患者的对照。

结果

牙髓石增加与II型糖尿病和高血压等代谢性疾病之间存在明确关系;同样,牙周健康不佳与牙髓石也显著相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4580/11329071/d5d9894eb8f3/JOMFP-28-192-g001.jpg

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