Suppr超能文献

改善 2 型糖尿病患者和有发展为 2 型糖尿病风险人群血糖控制的干预措施。

Interventions to improve glycaemic control in people living with, and at risk of developing type 2 diabetes.

机构信息

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

出版信息

Diabetes Obes Metab. 2024 Sep;26 Suppl 4:39-49. doi: 10.1111/dom.15855. Epub 2024 Aug 19.

Abstract

Type 2 diabetes mellitus is one of the most prevalent health conditions worldwide, affecting millions of individuals and posing significant public health challenges. Understanding the nature of type 2 diabetes, its causes, symptoms and treatments is crucial for managing and preventing its complications. Many different dietary strategies are used by individuals to treat and manage diabetes. This review provides an overview of popular dietary strategies that have evidence for improving long-term glycaemic control or achieving diabetes remission, as well as strategies that may be useful to reduce postprandial hyperglycaemia, which may be of use in the prevention of diabetes, but also as strategies for those already diagnosed but trying to manage their condition better. Recent clinical trials have provided evidence that in people living with type 2 diabetes who also live with overweight or obesity, using a total diet replacement weight loss programme results in significant and substantial weight loss, and as a result, many people can achieve remission from their diabetes. There has been considerable interest in whether similar effects can be achieved without reliance on formula foods, using real diet approaches. Reduced or low-carbohydrate diet approaches hold some promise, with observational or preliminary findings suggesting beneficial effects, but evidence from robust trials or systematic reviews of randomized controlled trials is still lacking. The Mediterranean dietary pattern, low in saturated fat and high in monounsaturated fat, also has some potential, with evidence to suggest some people can lose weight and achieve remission using this approach, which may be easier to adhere to longer term than more intensive total diet replacement and low-carbohydrate strategies. Plant-based diets that advocate for the elimination of animal-based and/or animal-derived foods have increased in popularity. There is evidence from epidemiological studies that people who follow these diets have a lower risk of developing type 2 diabetes, and evidence from trials and systematic reviews of trials that changing to a dietary pattern lower in animal-based and animal-derived foods has benefits on glycaemic control and other markers of cardiovascular disease. While these approaches all provide food or nutrient prescriptions, approaches that incorporate periods of fasting do not provide rules on the types of foods that can or cannot be consumed, but rather provide time windows of when to eat. Evidence suggests that these approaches can be as effective in achieving energy restriction and weight loss as approaches that advocate continuous energy restriction, and there is evidence for benefits on glycaemic control independent of weight loss. Finally, popular dietary strategies that may be useful to use or combine to help prevent postprandial hyperglycaemia include reducing the glycaemic index or glycaemic load of the diet, high-fibre diets, eating foods in a meal in the order vegetables > protein > carbohydrates, preloading or combining acids such as vinegar or lemon juice with meals and engaging in low-intensity aerobic exercise immediately after meals.

摘要

2 型糖尿病是全球最常见的健康问题之一,影响着数百万人,给公共卫生带来重大挑战。了解 2 型糖尿病的性质、病因、症状和治疗方法对于管理和预防其并发症至关重要。许多不同的饮食策略被个体用于治疗和管理糖尿病。本综述概述了一些流行的饮食策略,这些策略有证据表明可以改善长期血糖控制或实现糖尿病缓解,以及一些可能有助于降低餐后高血糖的策略,这些策略可能有助于预防糖尿病,也可用于那些已经被诊断出糖尿病但试图更好地控制病情的患者。最近的临床试验提供了证据,表明对于患有 2 型糖尿病且超重或肥胖的人群,使用全饮食替代减重方案可显著且大量减重,因此许多人可以从糖尿病中缓解。人们对是否可以在不依赖配方食品的情况下,通过真实的饮食方法实现类似的效果产生了浓厚的兴趣。减少或低碳水化合物饮食方法有一定的潜力,观察性或初步研究结果表明有有益的效果,但来自稳健试验或随机对照试验系统评价的证据仍然缺乏。地中海饮食模式,饱和脂肪含量低,单不饱和脂肪含量高,也有一定的潜力,有证据表明,一些人可以通过这种方法减肥并缓解糖尿病,与更强化的全饮食替代和低碳水化合物策略相比,这种方法可能更容易长期坚持。提倡消除动物源性和/或动物源性食物的植物性饮食越来越受欢迎。来自流行病学研究的证据表明,遵循这些饮食的人患 2 型糖尿病的风险较低,来自试验和试验系统评价的证据表明,改变以动物源性和动物源性食物较低的饮食模式对血糖控制和心血管疾病的其他标志物有好处。虽然这些方法都提供了饮食或营养素的处方,但包括禁食期的方法并没有规定可以或不能食用的食物类型,而是提供了进食的时间窗口。有证据表明,这些方法在实现能量限制和体重减轻方面与提倡持续能量限制的方法一样有效,并且有证据表明血糖控制的好处独立于体重减轻。最后,有助于预防餐后高血糖的有用的饮食策略包括降低饮食的血糖指数或血糖负荷、高纤维饮食、按蔬菜>蛋白质>碳水化合物的顺序进食、在用餐时预加载或混合醋或柠檬汁、以及在用餐结束后立即进行低强度有氧运动。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验