Sparano Clotilde, Rastrelli Giulia, Corona Giovanni, Vignozzi Linda, Vignoli Daniele, Maggi Mario
Endocrinology Unit, "Mario Serio" Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Andrology, Women's Endocrinology and Gender Incongruence Unit, "Mario Serio" Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Andrology. 2025 May;13(4):782-793. doi: 10.1111/andr.13738. Epub 2024 Aug 19.
Several robust epidemiological studies suggest that men are often engaged in sexual relationships with younger women with a variable, age-dependent age difference. However, the ageing process determines a significant worsening of the andrological status, which favors the onset of erectile dysfunction and hypogonadism.
To analyze the effects of differences in age between the partners [delta (Δ) age (M - F)] on patients referring to the Andrology Unit of Careggi University Hospital for male sexual dysfunction.
A monocentre cohort of 4055 male subjects was evaluated by SIEDY structured interview. The cross-sectional analysis assessed the psychobiological and relational correlates. The rate of forthcoming major cardiovascular events (MACE) was investigated in the longitudinal analysis. All the models have been adjusted for age, education, lifestyle, and chronic disease score.
∆ age (M-F) shows a stepwise increase, according to the increasing age bands of the male partner. ∆ age (M-F) was associated with a greater number of children, at the cost of more conflictual relationships within the family. The phenotype of these relationships is characterized by the report of a partner with a higher sexual desire and a higher ability to reach climax. Men seeking a younger partner show more often a histrionic personality (p = 0.023) and higher testosterone levels (p = 0.032). However, having a younger partner doesn't improve the ability to obtain a full erection. Kaplan-Maier analysis of a longitudinal subgroup of patients followed longitudinally (N = 1402) for 4.3 ± 2,59 years, showed that patients in the fourth quartile had a higher rate of forthcoming MACE versus those in the first quartile (p = 0.005).
In subjects with sexual dysfunctions (as in the general population) age-different relationships increase as a function of male ageing. A greater Δ age (M-F) is associated with specific men and relationship features and a higher risk of MACE.
多项有力的流行病学研究表明,男性常与年龄各异且存在年龄差的年轻女性建立性关系。然而,衰老过程会导致男性生殖系统状况显著恶化,这更易引发勃起功能障碍和性腺功能减退。
分析伴侣间年龄差异[年龄差(Δ)(男性 - 女性)]对前往卡雷吉大学医院男科就诊的男性性功能障碍患者的影响。
通过SIEDY结构化访谈对4055名男性受试者的单中心队列进行评估。横断面分析评估心理生物学和人际关系相关因素。纵向分析中调查即将发生的主要心血管事件(MACE)发生率。所有模型均针对年龄、教育程度、生活方式和慢性病评分进行了调整。
随着男性伴侣年龄组的增加,年龄差(男性 - 女性)呈逐步上升趋势。年龄差(男性 - 女性)与子女数量较多相关,但代价是家庭内部关系更具冲突性。这些关系的表型特征是报告称伴侣性欲更强且达到高潮的能力更高。寻求年轻伴侣的男性更常表现出表演型人格(p = 0.023)和较高的睾酮水平(p = 0.032)。然而,拥有年轻伴侣并不能提高获得完全勃起的能力。对1402名患者进行了4.3±2.59年纵向随访的纵向亚组的Kaplan - Maier分析表明,第四四分位数的患者即将发生MACE的发生率高于第一四分位数的患者(p = 0.005)。
在性功能障碍患者中(与普通人群一样),年龄差异关系随男性年龄增长而增加。更大的年龄差(男性 - 女性)与特定的男性和关系特征以及更高的MACE风险相关。