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结膜转位皮瓣治疗睑裂狭小综合征的长期疗效

Long-term Outcome of Conjunctival Transposition Flaps for Contracted Sockets.

作者信息

Vahdani Kaveh, Rose Geoffrey E

机构信息

Adnexal Service, Moorfields Eye Hospital, London, United Kingdom.

出版信息

Ophthalmic Plast Reconstr Surg. 2025;41(2):148-155. doi: 10.1097/IOP.0000000000002755. Epub 2024 Aug 19.

DOI:10.1097/IOP.0000000000002755
PMID:39158478
Abstract

PURPOSE

To assess the efficacy, and reintervention rate, of a conjunctival transposition technique in the treatment of contracted fornices in anophthalmic sockets.

METHODS

Retrospective case-note review of patients with contracted anophthalmic sockets who received a novel conjunctival mucosal transposition flap for augmentation of socket lining. Contracted anophthalmic sockets were categorized as grade 1 (minimal contraction), grade 2 (inferior and/or superior fornix), grade 3 (advanced scarring of the entire upper and lower fornices), and grade 4 (severe palpebral phimosis, recurrent cases, and irradiated sockets).

RESULTS

Of 32 patients (56% male), 53% had mild-to-moderate contracted anophthalmic sockets (grades 1 or 2). The transposition flap was combined with secondary ball implantation (3 cases), ball exchange (1 case), primary orbital floor (1 case), or revisional floor (3 cases) implantation. By an average follow up of 9.2 years, 16% (5 cases with grade 3 or 4) required additional relining, with another patient declining further surgery; this yielding an overall anatomic success of 81% (100% in grades 1 and 2; 60% in grades 3 and 4). At the last follow up, 91% of patients had adequate socket lining and 94% reported a comfortable socket with stable prostheses.

CONCLUSIONS

Having results similar to free grafting but without remote donor-site morbidity, this novel transposition flap satisfactorily addresses mild-to-moderate fornix contracture, and most patients achieve stable and comfortable prosthetic wear. Some patients with severe contracted anophthalmic sockets required further autologous grafting: this generally arose because the transposition flap included tissue from above the socket's horizontal raphé (with later contracture of the upper fornix).

摘要

目的

评估结膜转位技术治疗无眼球眼眶穹窿缩窄的疗效及再次干预率。

方法

对接受新型结膜黏膜转位瓣以增加眼眶内衬的无眼球眼眶穹窿缩窄患者进行回顾性病例笔记分析。无眼球眼眶穹窿缩窄分为1级(轻度收缩)、2级(下穹窿和/或上穹窿)、3级(上下穹窿均有严重瘢痕形成)和4级(严重睑裂狭窄、复发病例和放疗后眼眶)。

结果

32例患者(56%为男性)中,53%患有轻至中度无眼球眼眶穹窿缩窄(1级或2级)。转位瓣与二期球植入(3例)、球更换(1例)、一期眶底(1例)或修复眶底(3例)植入联合应用。平均随访9.2年,16%(5例3级或4级患者)需要再次内衬,另1例患者拒绝进一步手术;总体解剖学成功率为81%(1级和2级为100%;3级和4级为60%)。在最后一次随访时,91%的患者眼眶内衬合适,94%的患者报告眼眶舒适且义眼稳定。

结论

这种新型转位瓣的效果与游离移植相似,但无供区远期并发症,能令人满意地解决轻至中度穹窿挛缩问题,大多数患者义眼佩戴稳定且舒适。一些严重无眼球眼眶穹窿缩窄患者需要进一步自体移植:这通常是因为转位瓣包含了眼眶水平缝上方的组织(随后上穹窿挛缩)。

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