Department of Pediatrics, Division of Cardiology, Virgen del Rocío Children Hospital, Seville, Spain.
Department of Pediatrics, Division of Cardiology, Bristol Royal Hospital for Children, 3175 Chem. de la Côte-Sainte-Catherine, Montréal, QC H3T 1C5, Bristol, UK.
Eur J Pediatr. 2024 Oct;183(10):4553-4561. doi: 10.1007/s00431-024-05728-8. Epub 2024 Aug 19.
Pediatric cardiac symptoms such as palpitations, syncope, or seizure-like episodes pose diagnostic challenges for general pediatricians. These symptoms, though often benign, may reveal underlying arrhythmias or inherited cardiac conditions (ICCs), affecting the quality of life and limiting activity participation. The purpose of this study is to determine the effectiveness and safety of implantable loop recorders (ILRs) in diagnosing and managing arrhythmias in pediatric patients. A retrospective cohort study conducted over an 8-year period from January 2016 to December 2023 in a single pediatric cardiology center. A cohort of 155 pediatric patients (median age 11.4 years) who underwent ILR implantation were selected based on symptoms such as palpitations, chest pain, or syncope, and those with previously recorded arrhythmias or high-risk ICCs. The primary outcomes were the diagnostic yield of ILRs for arrhythmias and subsequent changes in patient management. Diagnostic yield was defined as the detection of relevant arrhythmias, such as pauses of 3 s or longer, high-degree AV block, sinus node dysfunction, supraventricular tachycardia, ventricular tachycardia, or inappropriate sinus tachycardia. The median follow-up period was 2.3 years (845 days). Diagnostic arrhythmias were recorded in 60% of patients with symptom-activated transmissions and 80% of device-activated transmissions. Sinus pauses (37.5%) and VT (30%) were the most common arrhythmias detected. In patients with syncope (n = 76), 30% had relevant arrhythmias. In the palpitations group (n = 20), 35% had relevant arrhythmias. Approximately 80% of patients with ILR-diagnosed arrhythmias underwent targeted management, including medication changes and additional procedures. No significant complications were observed; minor complications occurred in 2.5% of patients.Conclusions: New generation ILRs are effective and safe for diagnosing and managing pediatric arrhythmias, providing significant reassurance to patients and families. Further studies are needed to evaluate the impact of ILRs on quality of life and sports participation in high-risk young patients.
儿科心脏症状,如心悸、晕厥或类似癫痫发作的发作,对普通儿科医生来说具有诊断挑战性。这些症状虽然通常是良性的,但可能揭示潜在的心律失常或遗传性心脏疾病(ICC),影响生活质量并限制活动参与。本研究旨在确定植入式环路记录器(ILR)在诊断和管理儿科患者心律失常方面的有效性和安全性。
这是一项回顾性队列研究,在一个儿科心脏病中心进行,时间跨度为 2016 年 1 月至 2023 年 12 月,共 8 年。根据心悸、胸痛或晕厥等症状,选择了 155 名接受 ILR 植入的儿科患者(中位年龄 11.4 岁),并且这些患者之前记录有心律失常或高风险 ICC。主要结局是 ILR 对心律失常的诊断率以及随后患者管理的变化。诊断率定义为检测到相关心律失常,如 3 秒或更长时间的暂停、高度房室传导阻滞、窦房结功能障碍、室上性心动过速、室性心动过速或不适当窦性心动过速。中位随访期为 2.3 年(845 天)。症状激活传输中有 60%的患者和设备激活传输中有 80%的患者记录到诊断性心律失常。窦性暂停(37.5%)和 VT(30%)是最常见的检测到的心律失常。在有晕厥的患者(n=76)中,有 30%有相关心律失常。在心悸组(n=20)中,有 35%有相关心律失常。大约 80%的 ILR 诊断为心律失常的患者接受了靶向治疗,包括药物改变和其他程序。未观察到明显的并发症;2.5%的患者出现轻微并发症。
新一代 ILR 对于诊断和管理儿科心律失常是有效且安全的,为患者和家属提供了重要的安心。需要进一步研究来评估 ILR 对高危年轻患者生活质量和运动参与的影响。