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感染性骨长入骨盆固定植入物的取出及骨整合的微型计算机断层扫描分析:病例说明

Removal of infected bone in-growth pelvic fixation implants and microcomputed tomography analysis of osseous integration: illustrative case.

作者信息

Spence Bradley S, Godlewski Matthew W, Haselhuhn Jason J, Jones Kristen E, Polly David W

机构信息

Departments of Orthopedic Surgery, University of Minnesota, Minneapolis, Minnesota.

Departments of Neurosurgery, University of Minnesota, Minneapolis, Minnesota.

出版信息

J Neurosurg Case Lessons. 2024 Aug 19;8(8). doi: 10.3171/CASE24274.

DOI:10.3171/CASE24274
PMID:39159495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11337943/
Abstract

BACKGROUND

A novel pelvic fixation screw fusion device (iFuse Bedrock Granite implant) was designed to promote bony fusion through self-harvesting fenestrations throughout the outer screw shank. Bone on-growth and in-growth using this design have been demonstrated in a sheep model, but data from human subjects have not been reported. A 66-year-old medically complex female with 2 prior spine fusions developed spondylodiscitis cephalad to a prior fusion, requiring the removal of instrumentation, which included screw fusion devices.

OBSERVATIONS

Within this case report, the authors present a novel bone-preserving technique for the removal of well-fixed screw fusion devices. One screw backed out with a driver, and the other 3 had to be trephined out. One screw sheared off the T30 torque driver, implying a removal torque greater than 270 inch-lbs (30.5 Nm). In addition, the removed implants were analyzed using microcomputed tomography (micro-CT) and demonstrated bone on-growth, in-growth, and through-growth in all 4 screws.

LESSONS

Micro-CT clearly demonstrated osseous integration of the screw fusion devices and provided significant support for the use of these implants for lumbopelvic fixation. The authors' hope is that the novel bone-preserving technique will help other surgeons when faced with the difficult removal of well-fixed screw fusion devices. https://thejns.org/doi/10.3171/CASE24274.

摘要

背景

一种新型骨盆固定螺钉融合装置(iFuse Bedrock Granite植入物)旨在通过贯穿外螺钉杆的自采集开窗促进骨融合。在绵羊模型中已证明使用这种设计的骨长入和骨内生情况,但尚未报告来自人类受试者的数据。一名66岁患有多种内科疾病的女性,之前有2次脊柱融合手术史,在先前融合部位上方发生了脊椎椎间盘炎,需要取出包括螺钉融合装置在内的内固定器械。

观察结果

在本病例报告中,作者介绍了一种用于取出固定良好的螺钉融合装置的新型保骨技术。一个螺钉用螺丝刀拧出,另外3个螺钉必须用环钻钻出。一个螺钉切断了T30扭矩螺丝刀,这意味着取出扭矩大于270英寸磅(30.5牛米)。此外,使用微型计算机断层扫描(micro-CT)对取出的植入物进行分析,结果显示所有4个螺钉均有骨长入、骨内生和贯穿生长。

经验教训

Micro-CT清楚地显示了螺钉融合装置的骨整合情况,并为这些植入物用于腰骶骨盆固定提供了有力支持。作者希望这种新型保骨技术能在其他外科医生面临取出固定良好的螺钉融合装置这一难题时有所帮助。https://thejns.org/doi/10.3171/CASE24274 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/0a964654098b/CASE24274_figure_5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/91f08d09e0a1/CASE24274_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/599dec8adf0e/CASE24274_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/2acebe859d44/CASE24274_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/211a658c6ee7/CASE24274_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/0a964654098b/CASE24274_figure_5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/91f08d09e0a1/CASE24274_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/599dec8adf0e/CASE24274_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/2acebe859d44/CASE24274_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/211a658c6ee7/CASE24274_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe5/11337943/0a964654098b/CASE24274_figure_5.jpg

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本文引用的文献

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J Orthop Res. 2024 Aug;42(8):1820-1830. doi: 10.1002/jor.25820. Epub 2024 Mar 3.
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Randomized Trial of Augmented Pelvic Fixation in Patients Undergoing Thoracolumbar Fusion for Adult Spine Deformity: Initial Results from a Multicenter Randomized Trial.随机对照试验:对接受胸腰椎融合术治疗成人脊柱畸形的患者行增强骨盆固定的效果:一项多中心随机试验的初步结果。
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The importance of the bacterial spectrum in the clinical diagnostics and management of patients with spontaneous pyogenic spondylodiscitis and isolated spinal epidural empyema: a 20-year cohort study at a single spine center.
自发性化脓性脊柱骨髓炎和孤立性脊柱硬膜外脓肿患者临床诊断和治疗中细菌谱的重要性:单脊柱中心 20 年队列研究。
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Beta-lactam-resistant Staphylococcus aureus in spinal osteomyelitis and spondylodiscitis: current landscape in antibiotic resistance, treatment, and complications.脊柱骨髓炎和脊椎椎间盘炎中的耐β-内酰胺金黄色葡萄球菌:抗生素耐药性、治疗及并发症的现状
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Sacroiliac Joint Degeneration and Pain After Spinal Arthrodesis: A Systematic Review.骶髂关节退变与脊柱关节融合术后疼痛:系统评价。
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Eur Spine J. 2022 Feb;31(2):461-472. doi: 10.1007/s00586-021-07072-z. Epub 2022 Jan 15.
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A systematic review: characteristics, complications and treatment of spondylodiscitis.系统回顾:椎间盘炎的特征、并发症及治疗。
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