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约旦撤药和多重用药实践的现状与未来方向

Current Landscape and Future Directions of Deprescribing and Polypharmacy Practices in Jordan.

作者信息

Barakat Muna, Nassar Razan, Gharaibeh Lobna, Thiab Samar, Nashwan Abdulqadir J

机构信息

Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, Jordan.

Pharmacological and Diagnostic Research Center, Biopharmaceutics and Clinical Pharmacy Department, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.

出版信息

Med Princ Pract. 2024;33(6):505-518. doi: 10.1159/000541009. Epub 2024 Aug 19.

DOI:10.1159/000541009
PMID:39159605
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11631112/
Abstract

This review explores the current landscape and future directions of deprescribing and polypharmacy practices in Jordan. The prevalence of polypharmacy, defined as the concurrent use of multiple medications by an individual, has been increasing in recent years due to various factors, such as population aging and the greater availability of medications. However, polypharmacy can lead to adverse drug events, suboptimal medication adherence, increased healthcare costs, and reduced quality of life. Deprescribing, on the other hand, involves the discontinuation or reduction of unnecessary or potentially harmful medications to improve patient outcomes. The findings presented in this review highlight the current state of deprescribing and polypharmacy practices in Jordan, including factors influencing their prevalence. Additionally, it discusses the challenges healthcare professionals face in implementing deprescribing strategies and identifies potential solutions for enhancing these practices in Jordanian healthcare settings. Moreover, this paper provides insights into future directions for deprescribing and polypharmacy practices in Jordan. Overall, this review offers valuable insights into the current landscape of deprescribing and polypharmacy practices in Jordan while also providing recommendations for future directions to optimize medication management strategies that can ultimately benefit patient outcomes within a sound healthcare system framework.

摘要

本综述探讨了约旦减药和多重用药实践的现状及未来方向。多重用药的定义是个体同时使用多种药物,近年来由于人口老龄化和药物可及性提高等多种因素,其患病率一直在上升。然而,多重用药可能导致药物不良事件、用药依从性欠佳、医疗成本增加以及生活质量下降。另一方面,减药涉及停用或减少不必要或有潜在危害的药物,以改善患者预后。本综述呈现的研究结果突出了约旦减药和多重用药实践的现状,包括影响其患病率的因素。此外,它还讨论了医疗保健专业人员在实施减药策略时面临的挑战,并确定了在约旦医疗环境中加强这些实践的潜在解决方案。此外,本文还提供了约旦减药和多重用药实践未来方向的见解。总体而言,本综述为约旦减药和多重用药实践的现状提供了宝贵见解,同时也为未来方向提供了建议,以优化药物管理策略,最终在健全的医疗系统框架内使患者受益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b27/11631112/9acf347f22cf/mpp-2024-0033-0006-541009_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b27/11631112/9acf347f22cf/mpp-2024-0033-0006-541009_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b27/11631112/9acf347f22cf/mpp-2024-0033-0006-541009_F01.jpg

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本文引用的文献

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Polypharmacy and potentially-inappropriate medications are prevalent in the elderly cancer patients receiving systemic cancer therapy and they co-relate with adverse outcomes.在接受系统癌症治疗的老年癌症患者中,多药治疗和潜在不适当的药物很常见,它们与不良结局相关。
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Strengthening Primary Healthcare in Jordan for Achieving Universal Health Coverage: A Need for Family Health Team Approach.加强约旦的初级医疗保健以实现全民健康覆盖:采用家庭健康团队方法的必要性。
Healthcare (Basel). 2023 Nov 19;11(22):2993. doi: 10.3390/healthcare11222993.
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Pharmacist-driven deprescribing initiative in primary care.
药剂师主导的初级保健药物减量计划。
J Am Pharm Assoc (2003). 2024 Jan-Feb;64(1):139-145. doi: 10.1016/j.japh.2023.09.003. Epub 2023 Sep 16.
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Student Perspectives on the Pharmacist's Role in Deprescribing Opioids: A Qualitative Study.学生对药剂师在停用阿片类药物中作用的看法:一项定性研究。
Pharmacy (Basel). 2023 Jul 13;11(4):116. doi: 10.3390/pharmacy11040116.
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Clinical practice guideline for deprescribing opioid analgesics: summary of recommendations.临床实践指南:减少阿片类镇痛药剂量的建议摘要。
Med J Aust. 2023 Jul 17;219(2):80-89. doi: 10.5694/mja2.52002. Epub 2023 Jun 25.
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A Proposed Curricular Framework for an Interprofessional Approach to Deprescribing.一份关于减药的跨专业方法的课程框架提案。
Med Sci Educ. 2023 Feb 23;33(2):551-567. doi: 10.1007/s40670-022-01704-9. eCollection 2023 Apr.
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Teaching Deprescribing and Combating Polypharmacy in the Pharmacy Curriculum: Educational Recommendations from Thematic Analysis of Focus Groups.药学课程中减药及应对多重用药的教学:焦点小组主题分析的教育建议
Clin Pract. 2023 Mar 14;13(2):442-453. doi: 10.3390/clinpract13020040.
8
Attitude towards deprescribing and its association with frailty and complexity of medication regimen: A survey of older inpatients in a district health board in New Zealand.对减药的态度及其与虚弱和药物治疗方案复杂性的关系:新西兰地区卫生局老年住院患者的调查。
BMC Geriatr. 2023 Mar 23;23(1):166. doi: 10.1186/s12877-023-03878-2.
9
Healthcare professionals' perspectives of deprescribing in older patients at the end of life in hospice care: a qualitative study using the Theoretical Domains Framework.医护人员对终末期 Hospice 照护老年患者减药的看法:基于理论领域框架的定性研究。
Int J Pharm Pract. 2023 May 7;31(3):305-313. doi: 10.1093/ijpp/riad005.
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Pharmacist-led olaparib follow-up service for ambulatory ovarian cancer patients: A prospective study in a tertiary specialized cancer hospital in China.药剂师主导的奥拉帕利门诊卵巢癌患者随访服务:在中国一家三级专科癌症医院进行的前瞻性研究。
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