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气动视网膜固定术与玻璃体切除术治疗单孔孔源性视网膜脱离的复位率比较

Reattachment rate with pneumatic retinopexy versus pars plana vitrectomy for single break rhegmatogenous retinal detachment.

作者信息

Pecaku Aurora, Martins Melo Isabela, Shor Reut, Francisconi Carolina L M, Marafon Samara Barbara, Chaudhary Varun, Hillier Roxane Jo, Muni Rajeev H

机构信息

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.

出版信息

Br J Ophthalmol. 2024 Dec 17;109(1):113-118. doi: 10.1136/bjo-2023-324005.

Abstract

AIM

To assess the primary reattachment rate (PARR) in pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) meeting the Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomised Trial (PIVOT) criteria with a single break in detached retina.

METHODS

A post hoc analysis of two clinical trials. To be included, patients with primary RRD had to meet PIVOT criteria but could have only one break in the detached retina. Patients with additional pathology in the attached retina were included in a secondary analysis. The primary outcome was PARR following PnR versus PPV at 1-year postoperatively.

RESULTS

162 patients were included. 53% (86/162) underwent PnR and 47% (76/162) had a PPV. 99% (85/86) and 86.8% (66/76) completed the 1-year follow-up visits in the PnR and PPV groups, respectively. PARR was 88.2% (75/85) in the PnR group and 90.9% (60/66) in the PPV group (p=0.6) with a mean postoperative logMAR best-corrected visual acuity of 0.19±0.25 versus 0.34±0.37 (Snellen 20/30 vs 20/44) (p=0.01) each in the PnR and PPV groups, respectively.In an additional analysis of patients who were also allowed to have any pathology in the attached retina, the PARR was 85% (91/107) and 91.6% (66/72) in the PnR and PPV groups, respectively (p=0.18).

CONCLUSIONS

PnR and PPV provide similar long-term PARR in a substantial proportion of patients meeting PIVOT criteria with only a single break in the detached retina. Therefore, in patients meeting these specific criteria, PnR is an appropriate first-line therapy as it offers superior functional outcomes without compromising PARR.

摘要

目的

评估在符合气性视网膜固定术与玻璃体切除术治疗原发性孔源性视网膜脱离结果随机试验(PIVOT)标准且视网膜脱离仅有一处裂孔的孔源性视网膜脱离(RRD)患者中,气性视网膜固定术(PnR)与玻璃体切除术(PPV)的一期复位率(PARR)。

方法

对两项临床试验进行事后分析。纳入的原发性RRD患者必须符合PIVOT标准,但视网膜脱离处只能有一处裂孔。视网膜附着处有其他病变的患者纳入二次分析。主要结局是术后1年时PnR与PPV后的PARR。

结果

纳入162例患者。53%(86/162)接受了PnR,47%(76/162)接受了PPV。PnR组和PPV组分别有99%(85/86)和86.8%(66/76)完成了1年的随访。PnR组PARR为88.2%(75/85),PPV组为90.9%(60/66)(p = 0.6),PnR组和PPV组术后平均logMAR最佳矫正视力分别为0.19±0.25和0.34±0.37(Snellen视力表20/30对20/44)(p = 0.01)。在对视网膜附着处也允许有任何病变的患者进行的额外分析中,PnR组和PPV组的PARR分别为85%(91/107)和91.6%(66/72)(p = 0.18)。

结论

在符合PIVOT标准且视网膜脱离仅有一处裂孔的相当一部分患者中,PnR和PPV提供相似的长期PARR。因此,对于符合这些特定标准的患者,PnR是一种合适的一线治疗方法,因为它在不影响PARR的情况下提供了更好的功能结局。

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