• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于立体定向放射外科的医用 LINAC 质量保证测试的带有偏心孔的 3D 打印拟人头部体模的开发和验证。

Development and validation of 3D printed anthropomorphic head phantom with eccentric holes for medical LINAC quality assurance testing in stereotactic radiosurgery.

机构信息

Department of Mechanical Engineering, National Institute of Technology, Calicut, India.

Department of Radiation Oncology, MVR Cancer Center and Research Institute, Calicut, India.

出版信息

Med Eng Phys. 2024 Aug;130:104217. doi: 10.1016/j.medengphy.2024.104217. Epub 2024 Aug 2.

DOI:10.1016/j.medengphy.2024.104217
PMID:39160023
Abstract

Stereotactic Radiosurgery (SRS) for brain tumors using Medical Linear Accelerator (LINAC) demands high precision and accuracy. A specific Quality Assurance (QA) is essential for every patient undergoing SRS to protect nearby non-cancerous cells by ensuring that the X-ray beams are targeted according to tumor position. In this work, a water-filled generic anthropomorphic head phantom consisting of two removable parts with eccentric holes was developed using Additive Manufacturing (AM) process for performing QA in SRS. In the patient specific QA, the planned radiation dose using Treatment Planning System (TPS) was compared with the dose measured in the phantom. Also, the energy consistency of radiation beams was tested at 200 MU for different energy beams at the central and eccentric holes of the phantom using an ionization chamber. Experimentally examined results show that planned doses in TPS are reaching the target within a 5% deviation. The ratio of the dose delivered in the eccentric hole to the dose delivered to the central hole shows variations of less than 2% for the energy consistency test. The designed, low-cost water-filled anthropomorphic phantom is observed to improve positioning verification and accurate dosimetry of patient-specific QA in SRS treatment.

摘要

立体定向放射外科(SRS)使用医用线性加速器(LINAC)治疗脑肿瘤需要高精度和准确性。每个接受 SRS 治疗的患者都需要进行特定的质量保证(QA),以通过确保 X 射线束根据肿瘤位置进行靶向来保护附近的非癌性细胞。在这项工作中,使用增材制造(AM)工艺开发了一个由两个带偏心孔的可移动部分组成的充水通用人体头部体模,用于进行 SRS 中的 QA。在患者特异性 QA 中,使用治疗计划系统(TPS)计划的辐射剂量与在体模中测量的剂量进行了比较。此外,还使用电离室在体模的中心和偏心孔处测试了不同能量束在 200MU 时的能量一致性。实验检查结果表明,TPS 中的计划剂量在 5%的偏差内达到了目标。对于能量一致性测试,偏心孔中输送的剂量与输送到中央孔的剂量之比的变化小于 2%。观察到设计的低成本充水人体头部体模可改善 SRS 治疗中患者特异性 QA 的定位验证和精确剂量测定。

相似文献

1
Development and validation of 3D printed anthropomorphic head phantom with eccentric holes for medical LINAC quality assurance testing in stereotactic radiosurgery.用于立体定向放射外科的医用 LINAC 质量保证测试的带有偏心孔的 3D 打印拟人头部体模的开发和验证。
Med Eng Phys. 2024 Aug;130:104217. doi: 10.1016/j.medengphy.2024.104217. Epub 2024 Aug 2.
2
An integrated quality assurance phantom for frameless single-isocenter multitarget stereotactic radiosurgery.无框架单等中心多靶立体定向放射外科的一体化质量保证模体。
Phys Med Biol. 2020 Jun 10;65(11):115006. doi: 10.1088/1361-6560/ab8534.
3
3D printed heterogeneous paediatric head and adult thorax phantoms for linear accelerator radiotherapy quality assurance: from fabrication to treatment delivery.3D 打印的小儿头和成人胸部混合体模用于直线加速器放射治疗质量保证:从制作到治疗实施。
Biomed Phys Eng Express. 2024 Aug 29;10(5). doi: 10.1088/2057-1976/ad6f13.
4
Characterization of a novel 3D printed patient specific phantom for quality assurance in cranial stereotactic radiosurgery applications.用于颅立体定向放射外科应用质量保证的新型 3D 打印个体化体模的特性研究。
Phys Med Biol. 2019 May 10;64(10):105009. doi: 10.1088/1361-6560/ab1758.
5
Development of a 3D printed phantom for commissioning and quality assurance of multiple brain targets stereotactic radiosurgery.用于多脑靶立体定向放射外科的调试和质量保证的 3D 打印体模的开发。
Phys Eng Sci Med. 2024 Jun;47(2):455-463. doi: 10.1007/s13246-023-01374-w. Epub 2024 Jan 29.
6
The development and testing of a novel spherical radiotherapy phantom system for the commissioning and patient-specific quality assurance of mono-isocentric multiple mets SRS plans.一种新型球形放射治疗体模系统的开发和测试,用于单等中心多发转移瘤 SRS 计划的调试和患者特异性质量保证。
Med Phys. 2021 Jan;48(1):105-113. doi: 10.1002/mp.14565. Epub 2020 Nov 26.
7
Dosimetric performance of the Elekta Unity MR-linac system: 2D and 3D dosimetry in anthropomorphic inhomogeneous geometry.Elekta Unity MR-linac 系统的剂量学性能:人体非均匀几何形状的 2D 和 3D 剂量学。
Phys Med Biol. 2019 Nov 22;64(22):225009. doi: 10.1088/1361-6560/ab52ce.
8
Treatment planning system and beam data validation for the ZAP-X: A novel self-shielded stereotactic radiosurgery system.ZAP-X 治疗计划系统和射束数据验证:一种新型自屏蔽立体定向放射外科系统。
Med Phys. 2021 May;48(5):2494-2510. doi: 10.1002/mp.14740. Epub 2021 Apr 1.
9
Stereotactic radiosurgery with MLC-defined arcs: Verification of dosimetry, spatial accuracy, and end-to-end tests.立体定向放射外科治疗中使用多叶准直器定义的弧形:剂量学、空间准确性和端到端测试的验证。
J Appl Clin Med Phys. 2019 May;20(5):84-98. doi: 10.1002/acm2.12583. Epub 2019 Apr 11.
10
Dosimetric feasibility of brain stereotactic radiosurgery with a 0.35 T MRI-guided linac and comparison vs a C-arm-mounted linac.使用0.35 T MRI引导直线加速器进行脑部立体定向放射外科手术的剂量学可行性及与C形臂安装直线加速器的比较。
Med Phys. 2020 Nov;47(11):5455-5466. doi: 10.1002/mp.14503. Epub 2020 Oct 18.