Centers for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, RI 02906, USA.
Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI 02906, USA.
Mil Med. 2024 Aug 19;189(Suppl 3):306-313. doi: 10.1093/milmed/usae099.
Sexual and reproductive health is critical for the readiness of the warfighter, as costs of sexually transmitted infections and unintended pregnancy result in added health care costs, lost mission time, and impact on morale. The Multiphase Optimization Strategy (MOST) is an engineering-inspired framework used to optimize biobehavioral interventions. The Military Active-Duty Reproductive and Sexual Health (MARSH) research team applied the MOST framework to develop "Mission Wellness"-an electronic health intervention to promote sexual and reproductive health within the U.S. Military.
From 2017 to 2022, the MARSH team implemented the first and second phases of MOST to develop and optimize "Mission Wellness." All phases received institutional review board approval. The first phase consisted of expert and literature review, qualitative interviews, and beta testing to identify intervention components and the optimization objective and to inform study design. The second phase consisted of a factorial trial.
Figures 1-4 outline the research program approach, demographics of the sample, and format of the app. Service members who used the application found it to be acceptable and, overall, reported that it would be easier to talk to a sexual partner about risk behaviors and history at the post-intervention assessment compared to baseline. This iterative optimization approach using both local and strategic engagement enhanced program development and set the stage for dissemination and implementation efforts.
In line with the iterative nature of MOST, the lessons learned during the optimization trial led the MARSH team to return "Mission Wellness" to the preparation phase. The utilization of mixed (i.e., qualitative and quantitative) research methods and engagement with stakeholders at multiple levels of the military enterprise provided the information necessary to further optimize "Mission Wellness." This programmatic approach also provides a blueprint for the development of research design and testing in military health care balancing rigor and agility.
性与生殖健康对于作战人员的准备至关重要,因为性传播感染和意外怀孕的成本会导致额外的医疗保健费用、任务时间损失,并影响士气。多阶段优化策略(MOST)是一种受工程启发的框架,用于优化生物行为干预措施。军事现役生殖和性健康(MARSH)研究团队应用 MOST 框架开发了“任务健康”——一种电子健康干预措施,以促进美国军队中的性与生殖健康。
从 2017 年到 2022 年,MARSH 团队实施了 MOST 的第一和第二阶段,以开发和优化“任务健康”。所有阶段都获得了机构审查委员会的批准。第一阶段包括专家和文献综述、定性访谈和测试,以确定干预措施的组成部分和优化目标,并为研究设计提供信息。第二阶段包括因子试验。
图 1-4 概述了研究计划方法、样本人口统计学特征和应用程序格式。使用该应用程序的军人发现它是可以接受的,并且总体上报告说,与基线相比,在干预后评估中与性伴侣谈论风险行为和病史会更容易。这种使用本地和战略参与的迭代优化方法增强了项目的开发,并为传播和实施工作奠定了基础。
与 MOST 的迭代性质一致,优化试验期间吸取的教训促使 MARSH 团队将“任务健康”返回准备阶段。利用混合(即定性和定量)研究方法,并与军队企业多个层面的利益相关者接触,提供了进一步优化“任务健康”所需的信息。这种项目方法还为军事医疗保健中研究设计和测试的发展提供了蓝图,平衡了严谨性和灵活性。