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呼吸道合胞病毒:诊断挑战及其对老年人的影响:多学科专家组的建议。

Respiratory syncytial virus: challenges in diagnosis and impact on the elderly: Recommendations from a multidisciplinary panel.

机构信息

GSK, Rio de Janeiro, Brazil.

Laboratório de Virologia Clínica, Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), Disciplina de Infectologia, São Paulo, Brazil.

出版信息

Hum Vaccin Immunother. 2024 Dec 31;20(1):2388943. doi: 10.1080/21645515.2024.2388943. Epub 2024 Aug 19.

DOI:10.1080/21645515.2024.2388943
PMID:39161095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11340750/
Abstract

Respiratory syncytial virus (RSV) is an important cause of respiratory illness. While most attention is paid to childhood infection, the RSV burden in adults ≥60 y should also be considered. In Brazil, this is generally underrecognized, where greater focus is toward other respiratory pathogens. This article presents insights from a multidisciplinary panel gathered to review epidemiologic data and current diagnostic approaches to RSV in Brazil (and their limitations) and develop communication strategies to improve knowledge and awareness. National surveillance data indicate a steady increase in cases of RSV-related severe acute respiratory illness (RSV-SARI) in those aged ≥60 y in recent years, with high fatality rates (>30%). Routine RSV testing in older individuals with respiratory symptoms is relatively low. Educational activities targeted toward health-care professionals and the general public are critical to raising awareness of the importance of RSV in older individuals, particularly as protective vaccines are now available.

摘要

呼吸道合胞病毒(RSV)是一种重要的呼吸道疾病病原体。虽然大多数关注都集中在儿童感染上,但≥60 岁的成年人的 RSV 负担也应被考虑。在巴西,这种情况通常被低估了,因为人们更关注其他呼吸道病原体。本文介绍了一个多学科小组的观点,该小组聚集在一起,审查了巴西的 RSV 流行病学数据和当前的诊断方法(及其局限性),并制定了沟通策略,以提高对该疾病的认识和意识。国家监测数据表明,近年来,≥60 岁的人群因 RSV 相关严重急性呼吸道疾病(RSV-SARI)的病例稳步增加,病死率较高(>30%)。对有呼吸道症状的老年人进行常规 RSV 检测的比例相对较低。针对医疗保健专业人员和公众的教育活动对于提高人们对 RSV 在老年人中的重要性的认识至关重要,尤其是因为现在已经有了保护疫苗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/7840fa0a22a4/KHVI_A_2388943_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/a0a056258c0e/KHVI_A_2388943_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/93cc402162e4/KHVI_A_2388943_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/a72899d1e32a/KHVI_A_2388943_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/7840fa0a22a4/KHVI_A_2388943_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/a0a056258c0e/KHVI_A_2388943_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/93cc402162e4/KHVI_A_2388943_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/a72899d1e32a/KHVI_A_2388943_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70b1/11340750/7840fa0a22a4/KHVI_A_2388943_F0004_OC.jpg

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