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费尔蒂综合征的非典型表现:利妥昔单抗治疗成功——病例报告及文献综述

Atypical presentation of Felty syndrome: Successful management with rituximab therapy-A case report and review of literature.

作者信息

Iqbal Rabia, Colon-Ramos Ana, Hysenaj Zhenisa, Sinha Samridhi, Nabi Shahzaib, Marowa Sabrin

机构信息

Department of Internal Medicine The Brooklyn Hospital Center Brooklyn New York USA.

Department of Hematology and Oncology The Brooklyn Hospital Center Brooklyn New York USA.

出版信息

Clin Case Rep. 2024 Aug 18;12(8):e9339. doi: 10.1002/ccr3.9339. eCollection 2024 Aug.

Abstract

The atypical presentation of Felty syndrome, even without arthritis symptoms, needs further evaluation. Timely diagnosis of neutropenia and splenomegaly in patients with rheumatoid arthritis without joint symptoms is crucial for a better prognosis. Despite the rarity of the condition, clinicians should have a high index of suspicion, and multidisciplinary collaboration between rheumatology, hematology, and other specialists is required for accurate diagnosis.

摘要

费尔蒂综合征的非典型表现,即使没有关节炎症状,也需要进一步评估。对于没有关节症状的类风湿关节炎患者,及时诊断中性粒细胞减少和脾肿大对于改善预后至关重要。尽管这种情况罕见,但临床医生应保持高度怀疑,准确诊断需要风湿病学、血液学和其他专科之间的多学科协作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74c9/11331027/678bd213d166/CCR3-12-e9339-g002.jpg

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