Harris Rebecca Arden
Department of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Subst Use. 2024 Aug 16;18:29768357241272379. doi: 10.1177/29768357241272379. eCollection 2024 Jan-Dec.
To mitigate COVID-19 exposure risks in methadone clinics, the Substance Abuse and Mental Health Services Administration (SAMHSA) issued a temporary modification of regulations in March 2020 to permit, with state concurrence, extended take-home methadone doses. The modification allowed for up to 28 days of take-home methadone for stable patients and 14 days for those less stable. Using both interrupted time series and difference-in-differences methods, this study examined the association between the policy change and fatal methadone overdoses, comparing states that permitted the expansion of take-home doses with states that did not. The findings suggest the pandemic emergency take-home policy did not increase methadone-involved mortality.
为降低美沙酮诊所中新冠病毒暴露风险，物质滥用和精神健康服务管理局（SAMHSA）于2020年3月发布了一项法规临时修订案，经各州同意后，允许增加美沙酮带回家服用的剂量。此次修订允许病情稳定的患者最多可带回家28天剂量的美沙酮，病情不太稳定的患者则为14天剂量。本研究采用中断时间序列法和差分法，比较了允许增加带回家剂量的州与未允许的州，以此检验政策变化与美沙酮过量致死之间的关联。研究结果表明，疫情期间的紧急带回家政策并未增加美沙酮相关死亡率。
