Department of Public Policy and Public Affairs, John McCormack Graduate School of Policy and Global Studies, University of Massachusetts Boston, Boston, MA.
The Center for Global Health and Health Policy, Global Health and Education Projects, Inc., Riverdale, MD.
Ann Epidemiol. 2023 Jan;77:85-89. doi: 10.1016/j.annepidem.2022.11.007. Epub 2022 Nov 28.
During the COVID-19 pandemic, social and economic disruption such as social isolation, job and income losses, and increased psychological distress, may have contributed to the increase in drug-overdose mortality. This study aims to measure the impact of the pandemic on monthly trends in drug-overdose mortality in the United States.
We used the 2018-2020 final and 2021 provisional monthly deaths from the National Vital Statistics System and monthly population estimates from the Census Bureau to compute monthly mortality rates by age, sex, and race/ethnicity. We use log-linear regression models to estimate monthly percent increases in mortality rates from January 2018 through November 2021.
The age-adjusted drug-overdose mortality rate among individuals aged older than or equal to 15 years increased by 30% between 2019 (70,459 deaths) and 2020 (91,536 deaths). During January 2018-November 2021, the monthly drug-overdose mortality rate increased by 2.05% per month for Blacks, 2.25% for American Indians/Alaska Natives, 1.96% for Hispanics, 1.33% for Asian/Pacific Islanders, and 0.96% for non-Hispanic Whites. Average monthly increases in mortality were most marked among those aged 15-24 and 35-44 years.
The COVID-19 pandemic had a substantial impact on the rising trends in drug-overdose mortality during the peak months in 2020 and 2021.
在 COVID-19 大流行期间，社交隔离、失业和收入损失以及心理压力增加等社会经济破坏因素可能导致药物过量死亡率上升。本研究旨在衡量大流行对美国药物过量死亡率月度趋势的影响。
我们使用了 2018-2020 年最终和 2021 年暂定的国家生命统计系统每月死亡数据以及人口普查局的每月人口估计数据，按年龄、性别和种族/族裔计算每月死亡率。我们使用对数线性回归模型来估计 2018 年 1 月至 2021 年 11 月期间死亡率的每月百分比增长。
年龄调整后的 15 岁及以上人群的药物过量死亡率在 2019 年（70459 人死亡）和 2020 年（91536 人死亡）之间增加了 30%。在 2018 年 1 月至 2021 年 11 月期间，黑人的每月药物过量死亡率每月增加 2.05%，美国印第安人/阿拉斯加原住民增加 2.25%，西班牙裔增加 1.96%，亚洲/太平洋岛民增加 1.33%，非西班牙裔白人增加 0.96%。在 15-24 岁和 35-44 岁年龄段，死亡率的平均每月增幅最为显著。
COVID-19 大流行对 2020 年和 2021 年高峰月份药物过量死亡率上升趋势产生了重大影响。
