改善非梗阻性无精子症男性患者在显微睾丸精子提取术中精子获取的技术。
Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA.
作者信息
Kavoussi Parviz K, Atmoko Widi, Pinggera Germar-Michael
机构信息
Department of Reproductive Urology, Austin Fertility and Reproductive Medicine/Westlake IVF, Austin, TX 78746, USA.
Department of Urology, Faculty of Medicine, University of Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
出版信息
Asian J Androl. 2025 May 1;27(3):375-382. doi: 10.4103/aja202450. Epub 2024 Aug 16.
Nonobstructive azoospermia (NOA) is considered the most challenging clinical scenario for infertile men and current treatments leave many men unsuccessful at being able to achieve a pregnancy with their partner using their own sperm. Microdissection testicular sperm extraction (micro-TESE) is the choice for men with NOA desiring to father children with their own gametes. Micro-TESE results in the highest numbers of sperm cells retrieved for use with in vitro fertilization/intracytoplasmic sperm injection. With suboptimal micro-TESE success rates of sperm retrieval and then pregnancy and live birth using the retrieved sperm with in vitro fertilization/intracytoplasmic sperm injection, advances to improve outcomes are necessary. This article comprehensively reviews the technologies investigated to date to improve the outcomes for men undergoing micro-TESE.
非梗阻性无精子症（NOA）被认为是不育男性面临的最具挑战性的临床情况，目前的治疗方法使许多男性无法通过自身精子与伴侣成功受孕。显微外科睾丸精子提取术（micro-TESE）是希望用自身配子生育子女的NOA男性的选择。Micro-TESE能获取数量最多的精子细胞用于体外受精/卵胞浆内单精子注射。鉴于micro-TESE在精子获取以及随后使用获取的精子进行体外受精/卵胞浆内单精子注射的妊娠和活产成功率不尽人意，有必要改进技术以提高治疗效果。本文全面综述了迄今为止为改善接受micro-TESE男性的治疗效果而研究的技术。
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