Zhao Yuan-Qi, Li Nian, Jiang Xiao-Hua, Wan Yang-Yang, Xu Bo, Hu Xue-Chun, Hou Yi-Fu, Li Ji-Yan, Bai Shun
Wannan Medical College, Wuhu 241002, China.
Center for Reproduction and Genetics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.
Asian J Androl. 2025 Jan 1;27(1):90-95. doi: 10.4103/aja202461. Epub 2024 Aug 20.
A previous study showed that the length of the foreskin plays a role in the risk of sexually transmitted infections and chronic prostatitis, which can lead to poor quality of sexual life. Here, the association between foreskin length and sexual dysfunction was evaluated. A total of 5700 participants were recruited from the andrology clinic at The First Affiliated Hospital of University of Science and Technology of China (Hefei, China). Clinical characteristics, including foreskin length, were collected, and sexual function was assessed by the International Index of Erectile Function-5 (IIEF-5) and Premature Ejaculation Diagnostic Tool (PEDT) questionnaires. Men with sexual dysfunction were more likely to have redundant foreskin than men without sexual dysfunction. Among the 2721 erectile dysfunction (ED) patients and 1064 premature ejaculation (PE) patients, 301 (11.1%) ED patients and 135 (12.7%) PE patients had redundant foreskin, respectively. Men in the PE group were more likely to have redundant foreskin than men in the non-PE group ( P = 0.004). Logistic regression analyses revealed that the presence of redundant foreskin was associated with increased odds of moderate/severe ED (adjusted odds ratio [aOR] = 1.31, adjusted P = 0.04), moderate PE (aOR = 1.38, adjusted P = 0.02), and probable PE (aOR = 1.37, adjusted P = 0.03) after adjusting for confounding variables. Our study revealed a positive correlation between the presence of redundant foreskin and the risk of sexual dysfunction, especially in PE patients. Assessment of the length of the foreskin during routine clinical diagnosis may provide information for patients with sexual dysfunction.
先前的一项研究表明，包皮长度在性传播感染和慢性前列腺炎的风险中起作用，这可能导致性生活质量低下。在此，评估了包皮长度与性功能障碍之间的关联。总共从中国科学技术大学附属第一医院（合肥，中国）男科门诊招募了5700名参与者。收集包括包皮长度在内的临床特征，并通过国际勃起功能指数-5（IIEF-5）和早泄诊断工具（PEDT）问卷评估性功能。性功能障碍的男性比没有性功能障碍的男性更有可能有包皮过长。在2721例勃起功能障碍（ED）患者和1064例早泄（PE）患者中，分别有301例（11.1%）ED患者和135例（12.7%）PE患者有包皮过长。PE组的男性比非PE组的男性更有可能有包皮过长（P = 0.004）。逻辑回归分析显示，在调整混杂变量后，包皮过长与中度/重度ED（调整后的优势比[aOR]=1.31，调整后的P = 0.04）、中度PE（aOR = 1.38，调整后的P = 0.02）和可能的PE（aOR = 1.37，调整后的P = 0.03）的几率增加相关。我们的研究揭示了包皮过长的存在与性功能障碍风险之间的正相关，尤其是在PE患者中。在常规临床诊断期间评估包皮长度可能为性功能障碍患者提供信息。
