Brauer Philip R, Culbert August A, Zhang Emily, Xu James R, Ku Jamie A, Bottalico Danielle M, Ciolek Peter J, Genther Dane J, Fritz Michael A, Liu Sara W, Prendes Brandon L, Lamarre Eric D
From Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, U.S.A.
Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, U.S.A.
Laryngoscope. 2025 Feb;135(2):635-640. doi: 10.1002/lary.31708. Epub 2024 Aug 20.
To evaluate national trends in racial disparities for patients undergoing head and neck reconstructive surgery.
Retrospective analysis using the 2008 to 2021 American College of Surgeons National Surgical Quality Improvement Program database. Patients receiving microvascular free tissue transfer were eligible for inclusion. Pediatric patients and those treated by non-otolaryngologists were excluded. Outcomes were analyzed with univariate and multivariable models.
A total of 5831 head and neck free flap cases were analyzed, 4869 (83.5%) were White, 560 (9.6%) were Black or African American, and 402 (6.9%) were Asian, Native American, or other groups (ANAOG). The proportion of Black or African American patients and ANAOG patients undergoing free tissue transfer increased significantly over the time period (p = 0.047 and p = 0.010, respectively). However, there was a downtrend that started around 2017. In a multivariable model, Black or African American race was not associated with readmission (OR = 0.99 [95% CI 0.74, 1.31], p > 0.05), returning to the operating room (OR = 1.20 [95% CI 0.96, 1.49], p > 0.05), or any post-operative complication (OR = 0.83 [95% CI 0.68, 1.01], p > 0.05). There were also no significant associations found in the ANAOG population on multivariate analysis (p > 0.05 for all).
The percentage of free tissue transfer performed in patients from minority backgrounds with head and neck cancer has been increasing in the United States. Outcomes after head and neck microvascular reconstruction are similar when stratified by race. However, racial disparities remain and further work is necessary to reduce these disparities.
4 Laryngoscope, 135:635-640, 2025.
评估接受头颈重建手术患者种族差异的全国趋势。
使用2008年至2021年美国外科医师学会国家外科质量改进计划数据库进行回顾性分析。接受微血管游离组织移植的患者符合纳入标准。儿科患者和非耳鼻喉科医生治疗的患者被排除。采用单变量和多变量模型分析结果。
共分析了5831例头颈游离皮瓣病例,其中4869例(83.5%)为白人,560例(9.6%)为黑人或非裔美国人,402例(6.9%)为亚洲人、美洲原住民或其他群体(ANAOG)。在此期间,接受游离组织移植的黑人或非裔美国患者以及ANAOG患者的比例显著增加(分别为p = 0.047和p = 0.010)。然而,在2017年左右开始出现下降趋势。在多变量模型中,黑人或非裔美国种族与再次入院(OR = 0.99 [95% CI 0.74, 1.31],p > 0.05)、返回手术室(OR = 1.20 [95% CI 0.96, 1.49],p > 0.05)或任何术后并发症(OR = 0.83 [95% CI 0.68, 1.01],p > 0.05)均无关联。在多变量分析中,ANAOG人群中也未发现显著关联(所有p > 0.05)。
在美国,患有头颈癌的少数族裔背景患者接受游离组织移植的比例一直在增加。按种族分层时,头颈微血管重建后的结果相似。然而,种族差异仍然存在,需要进一步努力减少这些差异。
4 《喉镜》,135:635 - 640,2025年。