Thoyre Suzanne M, Park Jinhee, Crandell Jamie, Estrem Hayley, Knafl Kathleen, Wimmer John
Nurs Res. 2025;74(2):150-154. doi: 10.1097/NNR.0000000000000772. Epub 2024 Aug 16.
Infants with developmental risk factors are more likely to have feeding problems and develop chronic feeding disorders. Early detection and understanding of the progression of problematic feeding and its relationship with a child's biological functioning and the family feeding environment will enhance effective symptom management and development of interventions to prevent pediatric feeding disorders.
The New Through Two (NewThru2) feeding study protocol is described. Study aims are to (a) characterize symptoms of problematic feeding and trajectories of symptoms from predischarge from neonatal intensive care through 24 months of age, (b) determine the relationship of child biological function at discharge with symptom characteristics and trajectories, (c) describe the child's feeding environment and its relationship to symptoms from discharge through 24 months, and (d) determine the relationship between problematic feeding symptoms and growth and developmental outcomes.
NewThru2 is a prospective, longitudinal, mixed-method study following over 200 infants who received care in a neonatal intensive care unit and were identified as at risk for compromised development. The study follows enrolled infants through 24 months of age. Symptoms of problematic feeding are measured predischarge by clinical observation and medical record review and postdischarge by parent report. Biological function is measured by medical history and cardiorespiratory and autonomic nervous system function during feeding prior to discharge. Child feeding environment is measured by strategies parents use to manage feeding, the effect of feeding on the parent and family, and the use of feeding services. A subset of parents is interviewed to achieve a contextual understanding of the family feeding environment. Child outcome measures include parent-reported feeding skills and clinician-reported growth and neurodevelopment.
The results of this study will improve understanding of pediatric feeding disorders during a time of development sensitive to adequate nutrition and with infants at risk for developmental delays or impairments.
具有发育风险因素的婴儿更有可能出现喂养问题并发展为慢性喂养障碍。早期发现并了解问题喂养的进展及其与儿童生理功能和家庭喂养环境的关系,将有助于有效管理症状并制定干预措施以预防儿童喂养障碍。
描述“从新生儿期到两岁”(NewThru2)喂养研究方案。研究目标包括:(a)描述问题喂养的症状以及从新生儿重症监护病房出院前到24个月大时症状的发展轨迹;(b)确定出院时儿童的生理功能与症状特征及发展轨迹之间的关系;(c)描述儿童的喂养环境及其从出院到24个月期间与症状的关系;(d)确定问题喂养症状与生长发育结果之间的关系。
NewThru2是一项前瞻性、纵向、混合方法研究,跟踪200多名在新生儿重症监护病房接受治疗且被确定有发育受损风险的婴儿。该研究对入组婴儿进行跟踪直至24个月大。问题喂养的症状在出院前通过临床观察和病历审查进行测量,出院后通过家长报告进行测量。生理功能在出院前通过病史以及喂养期间的心肺和自主神经系统功能进行测量。儿童喂养环境通过家长用于管理喂养的策略、喂养对家长和家庭的影响以及喂养服务的使用情况来衡量。对一部分家长进行访谈以全面了解家庭喂养环境。儿童结局指标包括家长报告的喂养技能以及临床医生报告的生长发育和神经发育情况。
这项研究的结果将增进对儿童喂养障碍的理解,该阶段对于充足营养以及存在发育迟缓或损伤风险婴儿的发育至关重要。