Department of Cardiology and Pneumology, Georg-August University, University Medical Center, Göttingen, Germany.
Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Curr Cardiol Rep. 2024 Oct;26(10):1063-1076. doi: 10.1007/s11886-024-02110-w. Epub 2024 Aug 20.
This review aims to provide a profound overview on most recent studies on the clinical significance of Cardiovascular Computed Tomography (CCT) in diagnostic and therapeutic pathways. Herby, this review helps to pave the way for a more extended but yet purposefully use in modern day cardiovascular medicine.
In recent years, new clinical applications of CCT have emerged. Major applications include the assessment of coronary artery disease and structural heart disease, with corresponding recommendations by major guidelines of international societies. While CCT already allows for a rapid and non-invasive diagnosis, technical improvements enable further in-depth assessments using novel imaging parameters with high temporal and spatial resolution. Those developments facilitate diagnostic and therapeutic decision-making as well as improved prognostication. This review determined that recent advancements in both hardware and software components of CCT allow for highly advanced examinations with little radiation exposure. This particularly strengthens its role in preventive care and coronary artery disease. The addition of functional analyses within and beyond coronary artery disease offers solutions in wide-ranging patient populations. Many techniques still require improvement and validation, however, CCT possesses potential to become a "one-stop-shop" examination.
本次综述旨在对心血管计算机断层扫描(CCT)在诊断和治疗途径中的最新临床意义的研究进行全面的综述。由此,为在现代心血管医学中更广泛但有针对性地应用 CCT 铺平道路。
近年来,CCT 出现了新的临床应用。主要应用包括冠状动脉疾病和结构性心脏病的评估,并有国际主要学会的指南推荐。虽然 CCT 已经可以进行快速、非侵入性的诊断,但技术的改进使得使用具有高时间和空间分辨率的新型成像参数进行进一步深入评估成为可能。这些进展有助于诊断和治疗决策以及改善预后。本综述确定,CCT 的硬件和软件组件的最新进展允许进行高精确度、低辐射暴露的检查。这在预防保健和冠状动脉疾病方面尤其加强了 CCT 的作用。在冠状动脉疾病内外进行功能分析为广泛的患者群体提供了解决方案。然而,许多技术仍需要改进和验证,CCT 具有成为“一站式”检查的潜力。