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HerQLes 评分变化与客观疝结局的关联:ACHQC 数据库分析。

Association of changes in HerQLes scores with objective hernia outcomes: an analysis of the ACHQC database.

机构信息

Department of Surgery, University of Nebraska Medical Center, 983280 Nebraska Medical Center, Omaha, NE, 68198-3280, USA.

Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.

出版信息

Surg Endosc. 2024 Nov;38(11):6812-6826. doi: 10.1007/s00464-024-11140-y. Epub 2024 Aug 20.

Abstract

BACKGROUND

There are both objective and subjective measures of success following ventral hernia repair (VHR). Using the Abdominal Core Health Quality Collaborative (ACHQC) database, we sought to determine if there is an association between 30-day wound events (objective) and changes in the hernia-related quality-of-life (HerQLes) scores, (subjective). We hypothesized that patients who do not experience a 30-day wound event have a greater improvement in their HerQLes score over the short-term.

METHODS

All adult patients who underwent VHR with 30-day follow-up data available between 2013 and 2022 were identified within the ACHQC database. The 30-day wound events included surgical site infection (SSI), surgical site occurrence (SSO), and SSO requiring procedural intervention (SSOPI). The association between 30-day wound events and changes in HerQLes scores was measured using propensity matched score analysis. Further, regression analysis was used to determine if an improvement in HerQLes score at 30-days postoperatively was associated with the likelihood of experiencing a 30-day wound event.

RESULTS

Following a 3:1 matched analysis, 17,796 patients were available for analysis; 4449 (25%) patients experienced a 30-day wound event. The most common SSI was a superficial SSI and the most common SSO was a seroma. A 10-point improvement in the HerQLes score was statistically associated with a 3% decrease in SSI and a 4% decrease in the odds of experiencing an SSO. While not statistically significant, a 10-point improvement in the HerQLes score was associated with a 2.4% decrease in the odds of experiencing an SSOPI.

CONCLUSIONS

Subjective and objective measures of success following VHR seem to be correlated with one another over the short-term. Additional studies are needed to determine if this correlation exists with other subjective and objective measures of success and to determine if these correlations persist over the long-term. If present, these associations may help to guide patient counseling as experiencing a postoperative wound event following ventral hernia repair may not be detrimental to their quality-of-life over the long-term.

摘要

背景

腹疝修补术后(VHR)有客观和主观的成功衡量标准。我们使用腹部核心健康质量协作(ACHQC)数据库,旨在确定 30 天伤口事件(客观)与疝相关生活质量(HerQLes)评分变化(主观)之间是否存在关联。我们假设,在短期内,没有发生 30 天伤口事件的患者在 HerQLes 评分上的改善幅度更大。

方法

在 ACHQC 数据库中,确定了 2013 年至 2022 年期间接受 VHR 并具有 30 天随访数据的所有成年患者。30 天伤口事件包括手术部位感染(SSI)、手术部位发生(SSO)和需要手术干预的 SSO(SSOPI)。使用倾向评分匹配分析来衡量 30 天伤口事件与 HerQLes 评分变化之间的关系。此外,还进行了回归分析,以确定术后 30 天 HerQLes 评分的改善是否与发生 30 天伤口事件的可能性相关。

结果

经过 3:1 匹配分析,有 17796 例患者可供分析;4449 例(25%)患者发生了 30 天伤口事件。最常见的 SSI 是浅表性 SSI,最常见的 SSO 是血清肿。HerQLes 评分提高 10 分与 SSI 发生率降低 3%和发生 SSO 的几率降低 4%具有统计学相关性。虽然没有统计学意义,但 HerQLes 评分提高 10 分与发生 SSOPI 的几率降低 2.4%相关。

结论

VHR 术后的主观和客观成功衡量标准在短期内似乎相互关联。需要进一步的研究来确定这种相关性是否存在于其他主观和客观的成功衡量标准中,并确定这种相关性是否在长期内持续存在。如果存在,这些关联可能有助于指导患者咨询,因为腹疝修补术后发生术后伤口事件可能不会对患者的长期生活质量产生不利影响。

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