Department of Orthopedic Surgery, University Medical Center Utrecht, P. O. Box 85500, 3508, Utrecht, GA, The Netherlands.
Department of Orthopedics Isala, Zwolle, The Netherlands.
Spine Deform. 2024 Nov;12(6):1699-1707. doi: 10.1007/s43390-024-00925-9. Epub 2024 Aug 20.
Despite standardized biomechanical tests for spinal implants, we recently recognized pedicle screw failure to maintain the rod fixated as a clinical concern in scoliosis surgery. This occurrence study investigates the risk and magnitude of axial rod slip (ARS), its relation with technique and preventive measures.
Retrospective multicenter review of all primary scoliosis cases (2018-2020) with > 1 year FU from three centers, instrumented with uniplanar screws and 5.5 mm CoCr rods (Mesa 2, Stryker Corporation, Kalamazoo, MI, USA). ARS was defined as > 1 mm change in residual distal rod length from the screw in the lowest instrumented vertebra (LIV) and assessed by two independent observers. Slip distance, direction, relation to distal screw density and time of observation were recorded, as well as the effect of ARS on caudal curve increase. To prevent slip, more recent patients were instrumented with a different end-of-construct screw (Reline, NuVasive Inc. San Diego, CA, USA) and analyzed for comparison.
ARS risk was 27% (56/205) with a distance of 3.6 ± 2.2 mm, predominantly convex. 42% occurred before 4 months, the rest before 1 year. The caudal curve substantially increased three times more often in patients with ARS. Interobserver reliability was high and slip was in the expected direction. ARS was unrelated to distal screw density. Remarkable variation in ARS rates (53%, 31%, 13%) existed between the centers, while there was no difference in mean screw density (≈1.3 screws/level) or curve correction (≈60%). Revision surgery for ARS was required in 2.9% (6/207). Using the different end-of-construct screw, ARS risk was only 2% (1/56) and no revisions were required.
This study demonstrates the prevalence of axial rod slip at the end of construct in scoliosis surgery and its clinical relevance. While minimal ARS can be subclinical, ARS should not be mistaken for adding on. The most severe ARS predominantly occurred convex at the high-loaded distal screw when L3 was the LIV. Longer constructs (LIV L3 or L4) have a higher risk of ARS. The minimal risk of ARS with another end-of-construct screw underscores the influence of screw type on ARS occurrence in our series. Further research is essential to refine techniques and enhance patient outcomes.
尽管脊柱植入物的生物力学测试已经标准化,但我们最近认识到,在脊柱侧凸手术中,椎弓根螺钉固定杆的失败是一个临床关注的问题。本研究调查了轴向杆滑动(ARS)的风险和程度,以及其与技术和预防措施的关系。
回顾性分析了来自三个中心的所有原发性脊柱侧凸病例(2018-2020 年)的多中心回顾性研究,这些病例均接受了单侧螺钉和 5.5mm CoCr 杆(Mesa 2,Stryker Corporation,Kalamazoo,MI,USA)固定。ARS 定义为在最低固定椎(LIV)中从螺钉到残留远端杆的长度变化>1mm,并由两名独立观察者评估。记录了滑动距离、方向、与远端螺钉密度的关系以及观察时间,以及 ARS 对尾侧曲线增加的影响。为了防止滑动,最近的患者使用了不同的末端构建螺钉(Reline,NuVasive Inc.,圣地亚哥,CA,USA)进行了分析。
ARS 风险为 27%(56/205),距离为 3.6±2.2mm,主要为凸侧。42%的病例发生在 4 个月前,其余病例发生在 1 年前。ARS 患者的尾侧曲线增加了三倍以上。观察者间的可靠性很高,滑动方向也符合预期。ARS 与远端螺钉密度无关。三个中心之间的 ARS 发生率差异显著(53%、31%、13%),而平均螺钉密度(≈1.3 个/节段)或曲线矫正(≈60%)无差异。由于 ARS 进行翻修手术的比例为 2.9%(6/207)。使用不同的末端构建螺钉,ARS 风险仅为 2%(1/56),无需进行翻修。
本研究表明,脊柱侧凸手术中在构建末端出现轴向杆滑动是一种普遍存在且具有临床相关性的现象。虽然轻微的 ARS 可能是亚临床的,但不应将其误认为是附加的。最严重的 ARS 主要发生在高负荷的远端螺钉处,此时 L3 是 LIV。较长的构建物(LIV L3 或 L4)发生 ARS 的风险更高。另一种末端构建螺钉的 ARS 风险极小,这突出了螺钉类型对我们研究中 ARS 发生的影响。进一步的研究对于完善技术和提高患者的治疗效果至关重要。