Khalil Zeyad, Hanna Rafael A, Maher Soheir
College of Medicine, October 6 University, Cairo, EGY.
Emergency Medicine, Al-Fares Crystal Medical Complex, Makkah, SAU.
Cureus. 2024 Jul 21;16(7):e65039. doi: 10.7759/cureus.65039. eCollection 2024 Jul.
Idiopathic retroperitoneal fibrosis (IRF) is a rare condition characterized by fibrous tissue proliferation in the retroperitoneal space, commonly affecting the ureters and other abdominal structures. This case report describes a previously undocumented presentation of IRF in a 52-year-old female, who presented with recurrent gastrointestinal bleeding and severe anemia over six months. Diagnostic workup included endoscopy, colonoscopy, abdominal computed tomography (CT), and biopsy, revealing fibrous encasement of the mesenteric vessels leading to ischemic damage and gastrointestinal bleeding. Treatment involved high-dose corticosteroids and surgical resection of the fibrotic tissue, which resulted in complete resolution of symptoms. The aim of this case report is to highlight this unique presentation of IRF, discuss the diagnostic challenges, and explore effective treatment strategies for managing this rare but significant complication.
特发性腹膜后纤维化（IRF）是一种罕见疾病，其特征为腹膜后间隙纤维组织增生，常累及输尿管及其他腹部结构。本病例报告描述了一名52岁女性此前未被记录的IRF表现，该患者在六个月内反复出现胃肠道出血和严重贫血。诊断性检查包括内镜检查、结肠镜检查、腹部计算机断层扫描（CT）和活检，结果显示肠系膜血管被纤维组织包裹，导致缺血性损伤和胃肠道出血。治疗包括大剂量皮质类固醇和纤维化组织的手术切除，症状得以完全缓解。本病例报告的目的是突出IRF的这种独特表现，讨论诊断挑战，并探索有效治疗策略以处理这种罕见但严重的并发症。
