Suppr超能文献

客观性危机:使用个性化网络模型理解一名具有精神病性、情感性和强迫症状患者的适应不良意义建构

Crisis of objectivity: using a personalized network model to understand maladaptive sensemaking in a patient with psychotic, affective, and obsessive-compulsive symptoms.

作者信息

Oblak Aleš, Kuclar Matic, Horvat Golob Katja, Holnthaner Alina, Battelino Urška, Škodlar Borut, Bon Jurij

机构信息

Laboratory for Cognitive Neuroscience and Psychopathology, University Psychiatric Clinic Ljubljana, Ljubljana, Slovenia.

Department of Psychiatry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

出版信息

Front Psychol. 2024 Aug 6;15:1383717. doi: 10.3389/fpsyg.2024.1383717. eCollection 2024.

Abstract

INTRODUCTION

Psychiatric comorbidities have proven a consistent challenge. Recent approaches emphasize the need to move away from categorical descriptions of symptom clusters towards a dimensional view of mental disorders. From the perspective of phenomenological psychopathology, this shift is not enough, as a more detailed understanding of patients' lived experience is necessary as well. One phenomenology-informed approach suggests that we can better understand the nature of psychiatric disorders through personalized network models, a comprehensive description of a person's lifeworld in the form of salient nodes and the relationships between them. We present a detailed case study of a patient with multiple comorbidities, maladaptive coping mechanisms, and adverse childhood experiences.

METHODS

The case was followed for a period of two years, during which we collected multiple streams of data, ranging from phenomenological interviews, neuropsychological assessments, language analysis, and semi-structured interviews (Examination of Anomalous Self Experience and Examination of Anomalous World Experience). We analytically constructed a personalized network model of his lifeworld.

RESULTS

We identified an experiential category "the crisis of objectivity" as the core psychopathological theme of his lifeworld. It refers to his persistent mistrust towards any information that he obtains that he appraises as originating in his subjectivity. We can developmentally trace the crisis of objectivity to his adverse childhood experience, as well as him experiencing a psychotic episode in earnest. He developed various maladaptive coping mechanisms in order to compensate for his psychotic symptoms. Interestingly, we found correspondence between his subjective reports and other sources of data.

DISCUSSION

Hernan exhibits difficulties in multiple Research Domain Criteria constructs. While we can say that social sensorimotor, positive valence, and negative valence systems dysfunctions are likely associated with primary deficit (originating in his adverse childhood experience), his cognitive symptoms may be tied to his maladaptive coping mechanisms (although, they might be related to his primary disorder as well).

摘要

引言

精神疾病共病已被证明是一个持续存在的挑战。最近的方法强调需要从症状群的分类描述转向精神障碍的维度观。从现象学精神病理学的角度来看,这种转变是不够的,因为还需要更详细地了解患者的生活经历。一种受现象学启发的方法表明,我们可以通过个性化网络模型更好地理解精神疾病的本质,这是一种以显著节点及其之间的关系形式对一个人的生活世界的全面描述。我们展示了一个患有多种共病、适应不良应对机制和不良童年经历的患者的详细案例研究。

方法

对该病例进行了为期两年的跟踪,在此期间,我们收集了多方面的数据,包括现象学访谈、神经心理学评估、语言分析和半结构化访谈(异常自我体验检查和异常世界体验检查)。我们通过分析构建了他生活世界的个性化网络模型。

结果

我们确定了一个体验类别“客观性危机”作为他生活世界的核心精神病理学主题。它指的是他对任何他认为源于自身主观性的信息持续存在不信任。我们可以从发展角度将客观性危机追溯到他的不良童年经历,以及他认真经历的一次精神病发作。他发展出各种适应不良的应对机制以补偿他的精神病症状。有趣的是,我们发现他的主观报告与其他数据来源之间存在对应关系。

讨论

埃尔南在多个研究领域标准构建方面存在困难。虽然我们可以说,社会感觉运动、正性效价和负性效价系统功能障碍可能与主要缺陷(源于他的不良童年经历)相关,但他的认知症状可能与他的适应不良应对机制有关(尽管,它们也可能与他的原发性疾病有关)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b59b/11334081/764a8a56d38b/fpsyg-15-1383717-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验