• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

客观性危机:使用个性化网络模型理解一名具有精神病性、情感性和强迫症状患者的适应不良意义建构

Crisis of objectivity: using a personalized network model to understand maladaptive sensemaking in a patient with psychotic, affective, and obsessive-compulsive symptoms.

作者信息

Oblak Aleš, Kuclar Matic, Horvat Golob Katja, Holnthaner Alina, Battelino Urška, Škodlar Borut, Bon Jurij

机构信息

Laboratory for Cognitive Neuroscience and Psychopathology, University Psychiatric Clinic Ljubljana, Ljubljana, Slovenia.

Department of Psychiatry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

出版信息

Front Psychol. 2024 Aug 6;15:1383717. doi: 10.3389/fpsyg.2024.1383717. eCollection 2024.

DOI:10.3389/fpsyg.2024.1383717
PMID:39165762
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11334081/
Abstract

INTRODUCTION

Psychiatric comorbidities have proven a consistent challenge. Recent approaches emphasize the need to move away from categorical descriptions of symptom clusters towards a dimensional view of mental disorders. From the perspective of phenomenological psychopathology, this shift is not enough, as a more detailed understanding of patients' lived experience is necessary as well. One phenomenology-informed approach suggests that we can better understand the nature of psychiatric disorders through personalized network models, a comprehensive description of a person's lifeworld in the form of salient nodes and the relationships between them. We present a detailed case study of a patient with multiple comorbidities, maladaptive coping mechanisms, and adverse childhood experiences.

METHODS

The case was followed for a period of two years, during which we collected multiple streams of data, ranging from phenomenological interviews, neuropsychological assessments, language analysis, and semi-structured interviews (Examination of Anomalous Self Experience and Examination of Anomalous World Experience). We analytically constructed a personalized network model of his lifeworld.

RESULTS

We identified an experiential category "the crisis of objectivity" as the core psychopathological theme of his lifeworld. It refers to his persistent mistrust towards any information that he obtains that he appraises as originating in his subjectivity. We can developmentally trace the crisis of objectivity to his adverse childhood experience, as well as him experiencing a psychotic episode in earnest. He developed various maladaptive coping mechanisms in order to compensate for his psychotic symptoms. Interestingly, we found correspondence between his subjective reports and other sources of data.

DISCUSSION

Hernan exhibits difficulties in multiple Research Domain Criteria constructs. While we can say that social sensorimotor, positive valence, and negative valence systems dysfunctions are likely associated with primary deficit (originating in his adverse childhood experience), his cognitive symptoms may be tied to his maladaptive coping mechanisms (although, they might be related to his primary disorder as well).

摘要

引言

精神疾病共病已被证明是一个持续存在的挑战。最近的方法强调需要从症状群的分类描述转向精神障碍的维度观。从现象学精神病理学的角度来看,这种转变是不够的,因为还需要更详细地了解患者的生活经历。一种受现象学启发的方法表明,我们可以通过个性化网络模型更好地理解精神疾病的本质,这是一种以显著节点及其之间的关系形式对一个人的生活世界的全面描述。我们展示了一个患有多种共病、适应不良应对机制和不良童年经历的患者的详细案例研究。

方法

对该病例进行了为期两年的跟踪,在此期间,我们收集了多方面的数据,包括现象学访谈、神经心理学评估、语言分析和半结构化访谈(异常自我体验检查和异常世界体验检查)。我们通过分析构建了他生活世界的个性化网络模型。

结果

我们确定了一个体验类别“客观性危机”作为他生活世界的核心精神病理学主题。它指的是他对任何他认为源于自身主观性的信息持续存在不信任。我们可以从发展角度将客观性危机追溯到他的不良童年经历,以及他认真经历的一次精神病发作。他发展出各种适应不良的应对机制以补偿他的精神病症状。有趣的是,我们发现他的主观报告与其他数据来源之间存在对应关系。

讨论

埃尔南在多个研究领域标准构建方面存在困难。虽然我们可以说,社会感觉运动、正性效价和负性效价系统功能障碍可能与主要缺陷(源于他的不良童年经历)相关,但他的认知症状可能与他的适应不良应对机制有关(尽管,它们也可能与他的原发性疾病有关)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b59b/11334081/f8a473b61a14/fpsyg-15-1383717-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b59b/11334081/764a8a56d38b/fpsyg-15-1383717-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b59b/11334081/f8a473b61a14/fpsyg-15-1383717-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b59b/11334081/764a8a56d38b/fpsyg-15-1383717-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b59b/11334081/f8a473b61a14/fpsyg-15-1383717-g002.jpg

相似文献

1
Crisis of objectivity: using a personalized network model to understand maladaptive sensemaking in a patient with psychotic, affective, and obsessive-compulsive symptoms.客观性危机:使用个性化网络模型理解一名具有精神病性、情感性和强迫症状患者的适应不良意义建构
Front Psychol. 2024 Aug 6;15:1383717. doi: 10.3389/fpsyg.2024.1383717. eCollection 2024.
2
Letter to the Editor: CONVERGENCES AND DIVERGENCES IN THE ICD-11 VS. DSM-5 CLASSIFICATION OF MOOD DISORDERS.给编辑的信:《ICD-11 与 DSM-5 心境障碍分类的趋同与分歧》
Turk Psikiyatri Derg. 2021;32(4):293-295. doi: 10.5080/u26899.
3
Right care, first time: a highly personalised and measurement-based care model to manage youth mental health.精准医疗,首次就诊:高度个性化和基于评估的青少年心理健康管理医疗模式。
Med J Aust. 2019 Nov;211 Suppl 9:S3-S46. doi: 10.5694/mja2.50383.
4
Childhood emotional maltreatment, maladaptive coping and obsessive-compulsive symptoms in patients with obsessive-compulsive disorder.儿童期情感虐待、适应不良应对与强迫症患者的强迫症状。
Clin Psychol Psychother. 2023 May-Jun;30(3):620-630. doi: 10.1002/cpp.2829. Epub 2023 Jan 20.
5
Phenomenology of psychiatric emergencies.精神科急症的现象学
Front Psychol. 2023 Sep 12;14:1212054. doi: 10.3389/fpsyg.2023.1212054. eCollection 2023.
6
Letter to the Editor: EDUCATIONAL ACTIVITIES RELATED TO THE ICD-11 CHAPTER ON MENTAL DISORDERS.致编辑的信:与 ICD-11 精神障碍章节相关的教育活动。
Turk Psikiyatri Derg. 2021;32(4):291-292. doi: 10.5080/u26898.
7
Insight across mental disorders: A multifaceted metacognitive phenomenon.洞察精神障碍:一种多方面的元认知现象。
Psychiatriki. 2019 Jan-Mar;30(1):13-16. doi: 10.22365/jpsych.2019.301.13.
8
Psychopathological Functioning Levels (PFLs) and their possible relevance in psychiatric treatments: a qualitative research project.精神病理功能水平(PFLs)及其在精神科治疗中的潜在相关性:一项定性研究项目。
BMC Psychiatry. 2016 Jul 20;16:253. doi: 10.1186/s12888-016-0940-4.
9
Phenomenological Changes Associated with Deep Brain Stimulation for Obsessive Compulsive Disorder: A Cognitive Appraisal Model of Recovery.与深部脑刺激治疗强迫症相关的现象学变化:一种康复的认知评估模型
Brain Sci. 2023 Oct 10;13(10):1444. doi: 10.3390/brainsci13101444.
10
Depressing time: Waiting, melancholia, and the psychoanalytic practice of care压抑的时光:等待、忧郁与精神分析的关怀实践

本文引用的文献

1
Case report: Avoiding intolerance to antipsychotics through a personalized treatment approach based on pharmacogenetics.病例报告:通过基于药物遗传学的个性化治疗方法避免对抗精神病药物不耐受
Front Psychiatry. 2024 Mar 19;15:1363051. doi: 10.3389/fpsyt.2024.1363051. eCollection 2024.
2
A case report-"When less is more": controlled inpatient reduction of anticholinergic burden in a patient with clozapine-resistant schizophrenia.一例病例报告——“少即是多”:对一名氯氮平抵抗性精神分裂症患者进行住院期间抗胆碱能负担的控制性降低
Front Psychiatry. 2023 Jul 31;14:1222177. doi: 10.3389/fpsyt.2023.1222177. eCollection 2023.
3
Psychiatric comorbidity: a concept in need of a theory.
精神障碍共病:需要理论支撑的概念。
Psychol Med. 2023 Oct;53(13):5902-5908. doi: 10.1017/S0033291723001605. Epub 2023 Jun 2.
4
A study of doubt in obsessive-compulsive disorder.强迫症中怀疑的研究。
J Behav Ther Exp Psychiatry. 2023 Sep;80:101753. doi: 10.1016/j.jbtep.2022.101753. Epub 2023 Mar 13.
5
The SPEAK study rationale and design: A linguistic corpus-based approach to understanding thought disorder.SPEAK 研究的基本原理和设计:一种基于语言语料库的理解思维障碍的方法。
Schizophr Res. 2023 Sep;259:80-87. doi: 10.1016/j.schres.2022.12.048. Epub 2023 Jan 31.
6
Negative valence system as a relevant domain in compulsivity: review in a preclinical model of compulsivity.负性价系统作为强迫性的相关领域:强迫性临床前模型中的综述。
Emerg Top Life Sci. 2022 Dec 9;6(5):491-500. doi: 10.1042/ETLS20220005.
7
Using network models in person-centered care in psychiatry: How perspectivism could help to draw boundaries.在精神病学的以人为本的护理中使用网络模型:视角主义如何有助于划定界限。
Front Psychiatry. 2022 Sep 16;13:925187. doi: 10.3389/fpsyt.2022.925187. eCollection 2022.
8
What kind of science for dual diagnosis? A pragmatic examination of the enactive approach to psychiatry.双诊断需要怎样的科学?对精神病学具身认知方法的务实审视。
Front Psychol. 2022 Jul 18;13:825701. doi: 10.3389/fpsyg.2022.825701. eCollection 2022.
9
Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis.使用精神障碍跨诊断 mini-RDoC 评估对研究领域标准进行映射:验证性因子分析。
Eur Arch Psychiatry Clin Neurosci. 2023 Apr;273(3):527-539. doi: 10.1007/s00406-022-01440-6. Epub 2022 Jul 1.
10
Self-disorders and psychopathology: a systematic review.自我障碍与精神病理学:系统综述。
Lancet Psychiatry. 2021 Nov;8(11):1001-1012. doi: 10.1016/S2215-0366(21)00097-3.