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Dapagliflozin, peptide YY, and weight loss in heart failure with preserved ejection fraction.

作者信息

Reddy Yogesh N V, Melenovsky Vojtech, Asokan Aneesh K, Haluzik Martin, Carter Rickey E, Nair Sreekumaran, Jensen Michael D, Borlaug Barry A

机构信息

The Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, USA.

Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic.

出版信息

Eur Heart J. 2024 Oct 5;45(37):3889-3891. doi: 10.1093/eurheartj/ehae534.

DOI:10.1093/eurheartj/ehae534
PMID:39167062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11452744/
Abstract
摘要

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Circ Heart Fail. 2025 Aug;18(8):e012912. doi: 10.1161/CIRCHEARTFAILURE.125.012912. Epub 2025 May 29.
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本文引用的文献

1
Dapagliflozin and Right Ventricular-Pulmonary Vascular Interaction in Heart Failure With Preserved Ejection Fraction: A Secondary Analysis of a Randomized Clinical Trial.达格列净与射血分数保留的心力衰竭患者右心室-肺血管相互作用：一项随机临床试验的二次分析
JAMA Cardiol. 2024 Sep 1;9(9):843-851. doi: 10.1001/jamacardio.2024.1914.
2
Effects of Dapagliflozin on Body Composition and Its Relation to Hemodynamics in Heart Failure With Preserved Ejection Fraction.达格列净对射血分数保留的心力衰竭患者身体成分的影响及其与血流动力学的关系。
Circulation. 2024 Jun 18;149(25):2026-2028. doi: 10.1161/CIRCULATIONAHA.124.069479. Epub 2024 Jun 17.
3
Cardiac and Metabolic Effects of Dapagliflozin in Heart Failure With Preserved Ejection Fraction: The CAMEO-DAPA Trial.达格列净对射血分数保留的心力衰竭的心脏和代谢影响：CAMEO-DAPA 试验。
Circulation. 2023 Sep 5;148(10):834-844. doi: 10.1161/CIRCULATIONAHA.123.065134. Epub 2023 Aug 3.
4
Critical Analysis of the Effects of SGLT2 Inhibitors on Renal Tubular Sodium, Water and Chloride Homeostasis and Their Role in Influencing Heart Failure Outcomes.SGLT2 抑制剂对肾小管钠、水和氯稳态的影响及其影响心力衰竭结局的作用的批判性分析。
Circulation. 2023 Jul 25;148(4):354-372. doi: 10.1161/CIRCULATIONAHA.123.064346. Epub 2023 Jul 24.
5
Dapagliflozin for heart failure according to body mass index: the DELIVER trial.达格列净治疗心力衰竭与体重指数的相关性：DELIVER 试验。
Eur Heart J. 2022 Nov 1;43(41):4406-4417. doi: 10.1093/eurheartj/ehac481.
6
Effect of empagliflozin on circulating proteomics in heart failure: mechanistic insights into the EMPEROR programme.恩格列净对心力衰竭循环蛋白质组学的影响：对 EMPEROR 计划的机制见解。
Eur Heart J. 2022 Dec 21;43(48):4991-5002. doi: 10.1093/eurheartj/ehac495.
7
LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose.LX4211 通过减少钠/葡萄糖协同转运蛋白 1（SGLT1）介导的肠道葡萄糖吸收，增加血清胰高血糖素样肽 1 和肽 YY 水平。
J Pharmacol Exp Ther. 2013 May;345(2):250-9. doi: 10.1124/jpet.113.203364. Epub 2013 Mar 13.
8
Long-term persistence of hormonal adaptations to weight loss.体重减轻引起的激素适应的长期持续。
N Engl J Med. 2011 Oct 27;365(17):1597-604. doi: 10.1056/NEJMoa1105816.
9
Inhibition of food intake in obese subjects by peptide YY3-36.肽YY3-36对肥胖受试者食物摄入的抑制作用。
N Engl J Med. 2003 Sep 4;349(10):941-8. doi: 10.1056/NEJMoa030204.
10
Gut hormone PYY(3-36) physiologically inhibits food intake.肠道激素PYY(3-36)在生理上抑制食物摄入。
Nature. 2002 Aug 8;418(6898):650-4. doi: 10.1038/nature00887.