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局部麻醉下脊柱骨转移痛的双极射频消融术:患者体验和疼痛转归的可行性。

Bipolar Radiofrequency Ablation of Painful Spinal Bone Metastases Performed under Local Anesthesia: Feasibility Regarding Patient's Experience and Pain Outcome.

机构信息

Diagnostic and Interventional Neuroradiology Unit, CHUGA Grenoble Hospital, Université Grenoble Alpes, 38400 Saint Martin d'Heres, France.

Imagerie Medicale Pays D'agde, 34300 Agde, France.

出版信息

Medicina (Kaunas). 2021 Sep 15;57(9):966. doi: 10.3390/medicina57090966.

DOI:10.3390/medicina57090966
PMID:34577889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8466129/
Abstract

To assess the pain relief of bipolar RFA combined or not with vertebroplasty in patients with painful vertebral metastases and to evaluate the feasibility and tolerance of the RFA procedure performed under local anesthesia. : 25 patients (18 men, 7 women, mean age: 60.X y.o) with refractory painful vertebral metastasis were consecutively included between 2012 and 2019. A total of 29 radiofrequency ablation (RFA) procedures were performed under CT guidance, local anesthesia and nitrous oxide inhalation, including 16 procedures combined with vertebroplasty for bone consolidation purposes. Pain efficacy was clinically evaluated using the visual analogue scale (VAS) at day 1, 1 month, 3 months, 6 months and 12 months, and the tolerance of the procedure was evaluated. Procedure tolerance was graded as either not painful or tolerable in 97% of cases. Follow-up postprocedure mean VAS score decrease was 74% at day 1: 6.6 ( < 0.001), 79% at 1 month: 6.6 ( < 0.001), 79% at 3 months: 6.5 ( < 0.001), 77% at 6 months, and 79% at 12 months: 6.6 ( < 0.001). Bipolar RFA, with or without combined vertebroplasty, appears to be an effective and reliable technique for the treatment of refractory vertebral metastases in patients in the palliative care setting. It is a feasible procedure under local anesthesia which is well tolerated by patients therefore allowing to broaden the indications of such procedures. Field of study: interventional radiology.

摘要

评估双极射频消融术(RFA)联合或不联合椎体成形术治疗疼痛性椎体转移瘤的止痛效果,并评估局部麻醉下进行 RFA 手术的可行性和耐受性。

2012 年至 2019 年间,连续纳入 25 例(男 18 例,女 7 例,平均年龄:60.XX 岁)难治性疼痛性椎体转移瘤患者。共在 CT 引导下、局部麻醉和吸入一氧化二氮下进行了 29 次射频消融(RFA)手术,其中 16 次为增强骨整合目的而联合椎体成形术。在第 1 天、第 1 个月、第 3 个月、第 6 个月和第 12 个月,使用视觉模拟量表(VAS)对疼痛疗效进行临床评估,并评估手术的耐受性。

97%的病例中,手术耐受性评为无痛苦或可耐受。术后随访平均 VAS 评分第 1 天下降 74%:6.6(<0.001),第 1 个月下降 79%:6.6(<0.001),第 3 个月下降 79%:6.5(<0.001),第 6 个月下降 77%,第 12 个月下降 79%:6.6(<0.001)。

双极 RFA 联合或不联合椎体成形术治疗姑息治疗患者的难治性椎体转移瘤似乎是一种有效且可靠的技术。它是一种可行的局部麻醉下的手术,患者耐受性良好,因此可以扩大此类手术的适应证。研究领域:介入放射学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a30/8466129/599f2dd2a293/medicina-57-00966-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a30/8466129/680e416c585a/medicina-57-00966-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a30/8466129/d3ce2bcf75b5/medicina-57-00966-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a30/8466129/599f2dd2a293/medicina-57-00966-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a30/8466129/680e416c585a/medicina-57-00966-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a30/8466129/d3ce2bcf75b5/medicina-57-00966-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a30/8466129/599f2dd2a293/medicina-57-00966-g003.jpg

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