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[酒精依赖的长期病程]

[Long-term courses of alcohol dependence].

作者信息

John Ulrich, Rumpf Hans-Jürgen, Hoffmann Sabine, Meyer Christian, Kiefer Falk

机构信息

Institut für Community Medicine, Abteilung für Präventionsforschung und Sozialmedizin, Universitätsmedizin Greifswald, Greifswald, Deutschland.

Institut für Community Medicine, Abteilung für Präventionsforschung und Sozialmedizin, Universitätsmedizin Greifswald, Walther-Rathenau-Str. 48, 17475, Greifswald, Deutschland.

出版信息

Nervenarzt. 2025 Jan;96(1):31-36. doi: 10.1007/s00115-024-01719-0. Epub 2024 Aug 21.

Abstract

BACKGROUND

Descriptions of long-term histories of alcohol dependence provide insight into the etiology, prevention and care.

OBJECTIVE

Report of empirical findings about the development into and remission from alcohol dependence.

METHOD

Narrative literature review, analysis of findings from cohort studies in the general population.

RESULTS

Risk factors provide the opportunity to estimate increased probabilities of developing an alcohol dependence. Adolescents disclosed symptoms of alcohol dependence within 8 years after the first alcohol consumption. Alcohol dependence is related to a life expectancy 17.6 years fewer than in the general population. Data of a general population sample revealed a risk of early death 2.8 times higher than among people without mental disorders. The severity of alcohol dependence was shown to be a predictor of premature death. Nicotine dependence can add to the shortening of life in addition to alcohol dependence. Among the alcohol dependent residents in a general population sample, 90.2% did not have utilized detoxification treatment that included motivational treatment and 78.4% did not have utilized standard detoxification treatment in a psychiatric treatment facility. Remission without formal help has been proven. It is the main route of remission.

CONCLUSION

To reduce unfavorable courses of alcohol dependence, prevention and treatment should be focused more on the needs in the general population. In psychiatric and other medical routine care, screening and an appropriate brief intervention should be carried out.

摘要

背景

对酒精依赖长期病史的描述有助于深入了解其病因、预防和护理。

目的

报告关于酒精依赖的发展及缓解的实证研究结果。

方法

叙述性文献综述,分析普通人群队列研究的结果。

结果

风险因素为估计酒精依赖发生概率的增加提供了机会。青少年在首次饮酒后8年内出现酒精依赖症状。酒精依赖与预期寿命比普通人群少17.6年有关。普通人群样本数据显示,早死风险比无精神障碍者高2.8倍。酒精依赖的严重程度被证明是过早死亡的一个预测因素。除酒精依赖外,尼古丁依赖也会加剧寿命缩短。在普通人群样本中的酒精依赖者中,90.2%未接受包括动机治疗在内的解毒治疗,78.4%未在精神科治疗机构接受标准解毒治疗。已证实未经正规帮助也可实现缓解。这是缓解的主要途径。

结论

为减少酒精依赖的不良病程,预防和治疗应更多地关注普通人群的需求。在精神科及其他医疗常规护理中,应进行筛查和适当的简短干预。

相似文献

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[Long-term courses of alcohol dependence].[酒精依赖的长期病程]
Nervenarzt. 2025 Jan;96(1):31-36. doi: 10.1007/s00115-024-01719-0. Epub 2024 Aug 21.
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Stability of remission from alcohol dependence without formal help.无正规帮助情况下酒精依赖缓解的稳定性。
Alcohol Alcohol. 2006 May-Jun;41(3):311-4. doi: 10.1093/alcalc/agl008. Epub 2006 Feb 20.

本文引用的文献

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The Collaborative Study on the Genetics of Alcoholism: Overview.《酒精中毒遗传学协作研究》:概述。
Genes Brain Behav. 2023 Oct;22(5):e12864. doi: 10.1111/gbb.12864. Epub 2023 Sep 22.
5
Genetic nurture effects for alcohol use disorder.遗传对酒精使用障碍的影响。
Mol Psychiatry. 2023 Feb;28(2):759-766. doi: 10.1038/s41380-022-01816-z. Epub 2022 Oct 17.

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