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晚期慢性肾病公共援助接受者:来自日本具有创新肾病研究网络的研究者关于肾脏替代治疗选择及多种药物治疗的介绍见解

Recipients of public assistance with advanced chronic kidney disease: insights into receiving a presentation of kidney replacement therapy options and polypharmacy from Japanese investigators with innovative network about kidney disease study.

作者信息

Nakamura Yoshihiro, Sasaki Sho, Imaizumi Takahiro, Nishiwaki Hiroki, Murakami Minoru, Yazawa Masahiko, Raita Yoshihiko, Kawarazaki Hiroo, Shimizu Hideaki, Saka Yosuke, Takizawa Naoho, Fujita Yoshiro

机构信息

Department of Nephrology and Rheumatology, Chubu Rosai Hospital, Aichi, Japan.

Department of Nephrology, Nagoya University Graduate School of Medicine, Aichi, Japan.

出版信息

Clin Exp Nephrol. 2025 Jan;29(1):67-74. doi: 10.1007/s10157-024-02549-9. Epub 2024 Aug 22.

DOI:10.1007/s10157-024-02549-9
PMID:39168884
Abstract

BACKGROUND

The characteristics of patients with advanced chronic kidney disease (CKD) who are recipients of public assistance in Japan, and the adequacy of their medical care have not been reported previously.

METHODS

The records of patients with CKD stage G5 who visited nine facilities in Japan from April to June 2013 were retrospectively reviewed to compare the characteristics and care of recipients of public assistance with those of non-recipients. Receiving a presentation of kidney replacement therapy (KRT) options and polypharmacy were used as indicators of suboptimal medical care.

RESULTS

Of the 592 patients included in this analysis (mean age, 69.6 years; male, 59.3%), 56 (9.5%) were recipients of public assistance and 536 (90.5%) were non-recipients of public assistance. The prevalence of diabetes mellitus, unmarried status, and living alone were higher in recipients of public assistance. In multivariable logistic regression analysis, compared with non-recipients of public assistance, recipients of public assistance were less likely to receive a presentation of KRT options (adjusted odds ratio [aOR], 0.31; 95% confidence interval [CI], 0.17-0.56), and were more likely to receive ≥ 10 (aOR, 1.92; 95% CI, 1.05-3.51), and ≥ 15 (aOR, 2.78; 95% CI, 1.23-6.26) types of medication.

CONCLUSIONS

Patients with advanced CKD receiving public assistance were less likely to receive a presentation of KRT options and more likely to receive ≥ 10 and ≥ 15 types of medication, suggesting that recipients of public assistance are more likely to receive suboptimal medical care.

摘要

背景

此前尚未有关于日本接受公共援助的晚期慢性肾脏病(CKD)患者的特征及其医疗服务充分性的报道。

方法

回顾性分析2013年4月至6月期间在日本9家机构就诊的G5期CKD患者的记录,以比较接受公共援助者与未接受公共援助者的特征及医疗服务情况。接受肾脏替代治疗(KRT)方案介绍和使用多种药物被用作医疗服务不充分的指标。

结果

本分析纳入的592例患者(平均年龄69.6岁;男性占59.3%)中,56例(9.5%)接受公共援助,536例(90.5%)未接受公共援助。接受公共援助者中糖尿病、未婚及独居的患病率更高。在多变量逻辑回归分析中,与未接受公共援助者相比,接受公共援助者接受KRT方案介绍的可能性较小(调整优势比[aOR]为0.31;95%置信区间[CI]为0.17 - 0.56),且接受≥10种(aOR为1.92;95% CI为1.05 - 3.51)和≥15种(aOR为2.78;95% CI为1.23 - 6.26)药物治疗的可能性更大。

结论

接受公共援助的晚期CKD患者接受KRT方案介绍的可能性较小,接受≥10种和≥15种药物治疗的可能性更大,这表明接受公共援助者更有可能接受不充分的医疗服务。

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