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耐用型左心室辅助装置作为移植桥:一路上会有哪些期待?

Durable left ventricular assist devices as a bridge to transplantation: what to expect along the way?

机构信息

Division of Cardiology, Advanced Cardiac Care, Columbia University Irving Medical Center, New York, NY, USA.

Division of Cardiology, Montefiore Medical Center. Albert Einstein College of Medicine, New York, NY, USA.

出版信息

Expert Rev Med Devices. 2024 Sep;21(9):829-840. doi: 10.1080/17434440.2024.2393344. Epub 2024 Aug 28.

Abstract

INTRODUCTION

The scarcity of donors coupled with the improvements in left ventricular assist devices (LVAD) technology has led to the use of LVAD as a bridge to transplantation (BTT).

AREAS COVERED

The authors provide an overview of the current status of LVAD BTT implantation with special focus ranging from patient selection and pre-implantation optimization to post-transplant outcomes.

EXPERT OPINION

The United Network for Organ Sharing 2018 policy amendment resulted in a significant reduction in the number of LVADs used for BTT in the US. To overcome this issue, modifications in the US allocation policy to consider factors such as days on device support, age, and type of complications may be necessary to potentially increase implantation rates.

摘要

简介

供体的稀缺性加上左心室辅助设备(LVAD)技术的进步,导致 LVAD 被用作移植(BTT)的桥梁。

涵盖领域

作者提供了 LVAD BTT 植入的当前现状概述,特别关注从患者选择和植入前优化到移植后结果的范围。

专家意见

联合器官共享网络 2018 年的政策修正案导致美国用于 BTT 的 LVAD 数量显著减少。为了解决这个问题,可能需要对美国的分配政策进行修改,以考虑设备支持天数、年龄和并发症类型等因素,以提高潜在的植入率。

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